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Job-Art: Wissenschaftliche Jobausschreibungen

Master Position

Fachgebiet
Molecular Biology
Arbeitsstätte
Zentrum für Pathobiochemie und Genetik
Bewerbungsfrist
30.11.2017

Ausschreibungstext

Master position

 

 

The etiology of placental dysfunction is multifactorial with abundant gene and environment interactions. Placental dysfunctions are implicated in pregnancy complications such as gestational diabetes (GDM), pre-eclampsia (PE) and intrauterine growth restriction (IUGR). Based on our previous findings on the proteins involved in mercury kinetics from the healthy placenta, we now aim to compare their role and function in healthy and diseased placentas.

 

The employed techniques include basic cell culture methods, siRNA-mediated gene-knockdown, quantitative PCR, Immunoblotting, atomic fluorescence spectroscopy.

 

Starting date: As soon as possible

 

Duration: 6-12 months

 

Payment: Not provided

 

We are looking for a highly motivated, self-driven master student with a strong interest in cell biology and metal metabolism. If you are interested, please send your applications including a CV and letter of motivation as soon as possible to:

 

claudia.gundacker(at)meduniwien.ac.at

 

Further reading:

 

Balthasar, C., Stangl, H., Widhalm, R., Granitzer, S., Hengstschläger, M., Gundacker, C., 2017. Methylmercury Uptake into BeWo Cells Depends on LAT2-4F2hc , a System L Amino Acid Transporter. Int. J. Mol. Sci. 18. doi:10.3390/ijms18081730

 

Gundacker, C., Neesen, J., Straka, E., Ellinger, I., Dolznig, H., Hengstschläger, M., 2016. Genetics of the human placenta: implications for toxicokinetics. Arch. Toxicol. 90, 2563–2581. doi:10.1007/s00204-016-1816-6

 

Straka, E., Ellinger, I., Balthasar, C., Scheinast, M., Schatz, J., Szattler, T., Bleichert, S., Saleh, L., Knöfler, M., Zeisler, H., Hengstschläger, M., Rosner, M., Salzer, H., Gundacker, C., 2016. Mercury toxicokinetics of the healthy human term placenta involve amino acid transporters and ABC transporters. Toxicology 340, 34–42. doi:10.1016/j.tox.2015.12.005

Kontakt-Person(en)

Haupt-Kontakt
Name: Claudia Gundacker

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