- molecular biology, genetics
- MUW, Inst. f. Gefäßbiologie
Master positions are available for the Special Research Program SFB-F54 of the Austrian Science Fund (“Cellular Mediators Linking Inflammation and Thrombosis”;http://inthro.meduniwien.ac.at/?L=0) in the group of Prof. Johannes Schmid.
The master students will be integrated in a highly cooperative, supportive team with friendly working environment.
The transcription factor NF-κB is an essential player in inflammation and an important regulator of genes involved in thrombosis. Most of the signaling pathways that activate NF-κB, converge
at the level of IκB kinase 2 (IKK2), which phosphorylates inhibitory IκB molecules, triggering their polyubiquitination and proteasomal degradation. Based on the central role of IKK2 in the activation of NF-κB, we aimed at mimicking chronic inflammation in specific cell types of
genetically modified mice that are relevant for the vasculature: endothelial cells (ECs), macrophages and megakaryocytes, which are the precursor cells of platelets.
Depending on the specific project, the work will include cell culture (endothelial cells, macrophages, megakaryocytes), animal work, microscopy, flow cytometry and RNA/protein analysis.
If you are interested to apply and to become part of our team, please visit our website and send your Application and Curriculum Vitae to the following mail address:
- Name: Dr. Marion Mußbacher