- Host-Microbe Interactions
- Medical University of Vienna, Department for Cell & Developmental Biology
Host-Microbe interactions between Wolbachia and Drosophila,
Medical University of Vienna, Dept. Cell & Developmental Biology
The group of Wolfgang MILLER (https://anatomieundzellbiologie.meduniwien.ac.at/zellbiologie/developmental-biology/group-miller/) at Department of Cell and Developmental Biology of the Medical University of Vienna is looking for a highly motivated student interested in host microbe interactions between Wolbachia and Drosophila. Depending on time and interest of the candidate, the project could either be done as a shorter summer project, or be extended to a full Master’s thesis.
In the course of a research project funded by the Austrian Science Fund (FWF) the successful candidate will be integrated in our research group to decipher the impact of the endosymbiotic bacteria Wolbachia on genetics, physiology, sexual behavior and de novo speciation of the model system Drosophila.
This intracellular bacterium is well known as the prime reproductive parasite of insects by causing cytoplasmic incompatibilities, feminization, parthenogenesis or male killing, but depending on their evolutionary stage, it also can provide adaptive fitness benefits to insect hosts, such as nutritional provisioning or pathogen protection. We recently found that in some Drosophila species Wolbachia specifically colonize defined host brain regions that orchestrate sexual behavior of male and female flies. Furthermore we found that even slight perturbations of this intimate host-symbiont homeostasis can foster de novo speciation of Drosophila in the wild plus under experimental conditions in our laboratory.
The successful candidate will be embedded in the highly multidisciplinary and collaborative environments at the Department of Cell and Developmental Biology of the Medical University of Vienna.
Applicants should hold a bachelor's degree in biology, genetics, microbiology, or a related discipline. We are looking for enthusiastic scientists with proficient communication skills, who are good team players. Previous experiences with DNA & RNA techniques, sequence analyses, fly work, FISH assays, immunocytochemistry and/or microscopy techniques are advantageous.
Interested candidates please compile an application package containing
• A cover letter
• Your CV
• Contact details of two referees
and submit your application to the address below. Informal enquiries are welcome.
Applications will be reviewed on a rolling basis starting immediately until the position is filled. The starting date is flexible, the sooner the better.
Wolfgang Miller, Lab Genome dynamics, Center of Anatomy and Cell Biology, University of Vienna, Austria
Phone: 0043 1 40160 37750
- Name: Wolfgang Miller
- Telefon: 40160 37750