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Job-Art: Wissenschaftliche Jobausschreibungen

Master Thesis in Translational Science / Immunology

Fachgebiet
Immunology
Arbeitsstätte
Medical University of Vienna, Department of Rheumatology, Währinger Gürtel 18-20, 1090 Vienna
Website
Bewerbungsfrist
31.03.2020

Ausschreibungstext

We are looking for a highly motivated Master Student. The project aims to understand the interaction of T cells and fibroblasts, isolated from patients with Rheumatoid Arthritis. The project allows to get acquainted with the most recent techniques and to develop an understanding in experimental planning and data interpretation.

The RA synovial tissue is composed of a variety of cell types, including fibroblast-like synoviocytes (FLS) and T-cells. Deciphering the mechanism of interaction and its contribution to disease development and progression may pave the way towards novel therapeutic strategies against autoimmune diseases. We therefore established an experimental system, which allows studying T-cell – FLS interactions.

 

Tasks:

- Isolation of fibroblast-like synoviocytes from patient tissue

- Isolation of PBMCs from patient blood

- General maintenance of primary cell lines

- Assay setup and development

- (Fluorescence-) Microscopy including computerized image analysis

- Flow cytometry

- Western Blot/qRT-PCR

- RNA-sequencing (Library preparation and Basic analysis)

- The selected student will participate in group meetings and progress reports at our department

 

Supervision:

Maximilian Kugler (PhD Student)

Michael Bonelli (Principal Investigator)

 

Requirements:

- Bachelor degree in a relevant life science subject such as molecular biology, biochemistry, biotechnology or related studies

- Experience in sterile cell culture techniques as well as molecular biology methods (Western Blot, qRT-PCR,…)

- High accuracy in scientific work and its documentation

- Reliability

- Profound written and oral communication skills in English

 

Duration: 12 months incl. writing of the Master thesis

Location: Medical University of Vienna, Department of Rheumatology, Währinger Gürtel 18-20, 1090 Vienna

 

If you are interested to apply in order to become part of our team and to work in an outstanding research environment, you are welcome to submit your application including a CV indicating technical skills and a letter of motivation to: maximilian.kugler(at)meduniwien.ac.at

 

Contact:

Maximilian Kugler, MSc

PhD Student, Bonelli Lab (http://www.meduniwien.ac.at/rheumatologie/bonelli/)

Division of Internal Medicine III

Department of Rheumatology

Medical University of Vienna

Kontakt-Person(en)

Haupt-Kontakt
Name: Maximilian Kugler

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