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Job-Art: Wissenschaftliche Jobausschreibungen

Master Thesis Position

Fachgebiet
Cancer Research
Arbeitsstätte
Medical University of Vienna/Clinical Institute of Pathology
Bewerbungsfrist
31.01.2022

Ausschreibungstext

The research group of Prof. Lukas Kenner at the Clinical Institute of Pathology in Vienna is looking for a highly motivated master student interested in deciphering metabolic alterations that lead to therapy resistance in prostate cancer.

Prostate cancer (PCa) is the second most frequently diagnosed cancer in men. Even though the conventional treatment of androgen deprivation is initially effective, PCa patients develop metastasis and therapy resistance. It is known that cancer cells can adapt their energy metabolism according to the needs of the tumor and signals from the tumor microenvironment. A critical role is given here to the Warburg effect, which is one of the main hallmarks of cancer. However, PCa cells differ from all other tumor types by lacking the Warburg effect in the primary tumor stage.

The aim of this project is to decipher the metabolic changes occurring between therapy resistant PCa cells and treatment naïve cells in order to discover new therapeutical targets and regain therapy response. The work will deal with techniques of molecular biology including cell culture, metabolic analysis including omics techniques, animal work, immunohistochemistry, and RNA/protein analysis, etc.

The master student will be integrated in a highly cooperative, supportive team with friendly working environment. The master student will also have close collaboration with the Unit of Laboratory Animal Pathology at the Veterinary University of Vienna and the Institute of Pathology at the Medical University of Vienna.

We are looking for a motivated master student with a strong interest in cancer metabolism and therapy resistance, who is aiming at expanding her/his skills in the field of cancer research. Experience in basic tissue culture techniques and molecular biology would be of benefit. Students with a Bachelor's degree in biomedical sciences (biology, genetics, molecular biology, biochemistry, biotechnology) or a related discipline are welcome to apply. Furthermore, the dedicated master student should be a team player and be able to communicate in English, as we are an international research group.

Starting date: February/March 2022

Application deadline: 31.01.2022

The master thesis project includes a monthly research fellowship of € 460,66 EUR/month (according to the scales of the Austrian Science Fund FWF).

If you are interested to become part of our team and to work in an outstanding research environment, you are welcome to submit your application including a CV and a motivation letter to: emine.atas(at)meduniwien.ac.at

Kontakt-Person(en)

Haupt-Kontakt
Name: Emine Atas

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