Research technician (m/f/d) in Molecular Medicine/Cancer Research, 20h/week
- Molecular Medicine
- Medical University of Vienna
The role of the G-protein coupled receptor CALCRL in stemness and therapy resistance of AML
Recent work by ourselves and others has revealed the G-protein coupled receptor CALCRL as a novel key player in therapy resistance and stem cell properties of acute myeloid leukemia (AML). In the context of a project funded by the Austrian Science Fund, the role of CALCRL as a potential therapeutic target in AML is being further explored. All experiments are based on the mouse as a model system for human AML. They involve isolation of murine bone marrow cells, their transduction with retroviral vectors, transplantation into recipient mice, and subsequent in vivo and ex vivo assays. Animal handling, cell culture, transfections and retroviral transductions, molecular cloning, flow cytometry, immunoblot analysis, microscopy, and qRT-PCR will be the most important methods.
Work will be carried out in the group of Prof. Dr. Rotraud Wieser, Department of Oncology, Clinic of Medicine I, Medical University of Vienna, in close association with postdoctoral researcher Dr. Vladislav Strmiska. The small, highly interactive research team is embedded in the research communities of the Anna Spiegel Center of Translational Research and of the Translational Research Unit of the Department of Oncology.
around September 2022
a 3 year position with salary according to the "Kollektivvertrag", a friendly and supportive work atmosphere, and well-equipped laboratories and facilities.
Applicants should have attended a school/college for chemical engineering, hold a Bachelor in the biological sciences, or have an equivalent education. They should have practical laboratory experience with some of the above mentioned methods. They should have organizational skills, be good team players, and be comfortable using English as a working language.
How to apply:
Please send a CV and the name and contact details (e-mail address and telephone number) of 2-3 references to rotraud.wieser(at)meduniwien.ac.at.
- Name: Ao. Univ. Prof. Dr. Rotraud Wieser