Background:

Mucinous ovarian cancer (MOC) is a rare epithelial cancer and is not well investigated. Patients have poor prognosis due to the lack of specific treatment. Most of the MOCs harbor mutations in the KRAS gene. Different drugs have been developed to target the KRAS-related pathways.

Objectives:

• to test selected drugs on MOC

• to define the pathways interfered by the tested drugs

• to define the possible clinical use of the drugs

Techniques:

Experimental techniques include cell biology (cell culture, orgnoids culture, apoptosis assay, fluorescence-based assays to measure cell viability/death, live imaging assays), genetics (DNA/RNA extraction, Sanger sequencing, digital droplet PCR), molecular biology (RT-qPCR, Western blotting, RNA sequencing and data analyses, IHC, IF).

Qualification:

Master student in molecular biology, biomedical science or in other relevant fields; good basic knowledge of molecular biology; strong analytic capacity and commitment, as well as interest in science; web-lab experiences in cancer research or related fields;

Application:

Send examination record for Bachelor study and for Master study so far; a motivation letter; and CV to the email address above.

Fachgebiet

Molecular biology; Cancer research; Drug testing

Arbeitgeber

MUW

Arbeitsstätte

Research group Translational Gynecology; Department of Obstetrics and Gynecology

Antrittsdatum

01. Juli 2025

Bewerbungsfrist

30. Juni 2025

Kontakt

Prof. Dr. Dan Cacsire Castillo-Tong
dan.cacsire-castillo(at)meduniwien.ac.at
+43-1-40400-78330

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