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Circular Bioengineering

Circular Bioengineering

Roland Ludwig (ORCID: 0000-0002-5058-5874)
  • Grant DOI 10.55776/COE17
  • Funding program Clusters of Excellence
  • Status ongoing
  • Start December 1, 2024
  • End November 30, 2029
  • Funding amount € 16,150,361
  • E-mail

Disciplines

Biology (20%); Chemistry (10%); Industrial Biotechnology (55%); Economics (15%)

Keywords

    Bioengineering, Biocatalysis, Renewable Substrates, Circularity, Sustainable Processes, Bioeconomy

Abstract

The advancement of modern society depends on access to a wide range of essential goods, from medicines and food to energy, textiles, and consumer products. Since the Industrial Revolution, technological innovations have enabled the large-scale manufacturing of these goods, fueling rapid population growth and improving quality of life. However, this progress has come with significant environmental costs. Most current manufacturing processes heavily depend on non-renewable fossil fuels and employ methods that can be toxic, polluting, and unsustainable. These processes generally follow a `take, use, and throw away` model, where resources are used once and then discarded. To address the urgent environmental challenges we face, there is a growing need to shift toward sustainable production practices. Bioengineering, a field that merges biology, engineering, and the physical sciences, plays a crucial role in this transformation by developing technologies that align with the principles of environmental sustainability. By harnessing biological systems, bioengineering enables the design and production of goods in ways that are cleaner, safer, and more compatible with natural ecosystems. Coupling these mild approaches with the efficient use of renewable resources as starting materials and the recycling of the molecules and materials produced ultimately promises to create a closed-loop system. Such a system requires fewer raw materials, generates less waste, and ultimately reduces the environmental impactan approach in line with the concept of circularity. Our Cluster of Excellence is dedicated to accelerating the development of circular bioengineering by bringing together world-leading researchers from various disciplines to foster innovation. This collaborative effort focuses on four key research programs: i) utilizing renewable feedstocks to create materials that can be fully recycled, ii) designing biotechnological tools that capture and repurpose CO2 and waste streams, iii) developing sustainable production methods for chemicals using biological tools and iv) assessing the environmental and socio-economic impacts of these innovations to ensure true sustainability. This collaborative effort involves multiple universities, including the University of Natural Resources and Life Sciences, Vienna (BOKU), the University of Graz, the Technical University of Graz, the University of Vienna, and the Technical University of Vienna. By uniting experts from diverse fields, the Circular Bioengineering Cluster of Excellence is committed to pioneering research and innovation in circular bioengineering as well as to actively engaging with the public, industry professionals, and policymakers. Together, we aim to create a more sustainable and resilient future for all.

Consortium
  • Gunda Köllensperger, Universität Wien
    Board of Directors (01.12.2024 -)
  • Roland Ludwig, Universität für Bodenkultur Wien
    Director of Research (01.12.2024 -)
  • Wolfgang Kroutil, Universität Graz
    Board of Directors (01.12.2024 -)
  • Bernd Nidetzky, Technische Universität Graz
    Board of Directors (01.12.2024 -)
  • Marko D. Mihovilovic, Technische Universität Wien
    Board of Directors (01.12.2024 -)
  • Antje Potthast, Universität für Bodenkultur Wien
    Board of Directors (01.12.2024 -)
  • Chris Oostenbrink, Universität für Bodenkultur Wien
    Board of Directors (01.12.2024 -)
Key Researchers
  • Regina Kratzer, Technische Universität Graz (14.11.2024 -)
  • Robert Kourist, Technische Universität Graz (14.11.2024 -)
  • Florian Rudroff, Technische Universität Wien (14.11.2024 -)
  • Katharina Schröder, Technische Universität Wien (14.11.2024 -)
  • Matthias Georg Steiger, Technische Universität Wien (14.11.2024 -)
  • Oliver Spadiut, Technische Universität Wien (14.11.2024 -)
  • Ruth Birner-Grünberger, Technische Universität Wien (14.11.2024 -)
  • Hermine Mitter, Universität Graz (14.11.2024 -)
  • Katalin Barta Weissert, Universität Graz (14.11.2024 -)
  • Melanie Hall, Universität Graz (14.11.2024 -)
  • Alexander Bismarck, Universität Wien (14.11.2024 -)
  • Jürgen Zanghellini, Universität Wien (14.11.2024 -)
  • Robert Woodward, Universität Wien (14.11.2024 -)
  • Brigitte Gasser, Universität für Bodenkultur Wien (14.11.2024 -)
  • Diethard Mattanovich, Universität für Bodenkultur Wien (14.11.2024 -)
  • Doris Ribitsch, Universität für Bodenkultur Wien (14.11.2024 -)
  • Helga Lichtenegger, Universität für Bodenkultur Wien (14.11.2024 -)
  • Johannes Konnerth, Universität für Bodenkultur Wien (14.11.2024 -)
  • Johannes Schmidt, Universität für Bodenkultur Wien (14.11.2024 -)
  • Karlheinz Erb, Universität für Bodenkultur Wien (14.11.2024 -)
  • Notburga Gierlinger, Universität für Bodenkultur Wien (14.11.2024 -)
  • Stefan Hofbauer, Universität für Bodenkultur Wien (14.11.2024 -)
  • Stephan Hann, Universität für Bodenkultur Wien (14.11.2024 -)
  • Thomas Rosenau, Universität für Bodenkultur Wien (14.11.2024 -)
Research institution(s)
  • Technische Universität Graz - 12%
  • Universität Graz - 12%
  • Universität für Bodenkultur Wien - 37%
  • Technische Universität Wien - 21%
  • Universität Wien - 18%

Research Output

  • 3 Publications
Publications
  • 2025
    Title Advancing yeast metabolism for a sustainable single carbon bioeconomy
    DOI 10.1093/femsyr/foaf020
    Type Journal Article
    Author Kuzman M
    Journal FEMS Yeast Research
    Link Publication
  • 2025
    Title Minimal cut sets in metabolic networks: from conceptual foundations to applications in metabolic engineering and biomedicine
    DOI 10.1093/bib/bbaf188
    Type Journal Article
    Author Klamt S
    Journal Briefings in Bioinformatics
    Link Publication
  • 2025
    Title Increased antioxidative defense and reduced advanced glycation end-product formation by metabolic adaptation in non-small-cell-lung-cancer patients
    DOI 10.1038/s41467-025-60326-y
    Type Journal Article
    Author Tomin T
    Journal Nature Communications
    Pages 5157
    Link Publication

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