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Investigation of a novel SLM-BMG for knee implants

Investigation of a novel SLM-BMG for knee implants

Fereshteh Sourani (ORCID: 0000-0002-7165-7371)
  • Grant DOI 10.55776/ESP453
  • Funding program ESPRIT
  • Status ongoing
  • Start October 1, 2023
  • End September 30, 2026
  • Funding amount € 316,037

Disciplines

Mechanical Engineering (20%); Medical Engineering (20%); Nanotechnology (15%); Materials Engineering (45%)

Keywords

    Bulk Metallic Glass, Selective Laser Melting, Corrosion, Tribocorrosion, Biocompatibility, Cytotoxicity

Abstract

The project will investigate novel Selective Laser Melted Bulk Metallic Glass alloys for knee implants. The motivation behind this research stems from the high prevalence of knee-related issues, such as arthritis and injuries, which often require total joint replacements. The research will directly address the limitations of existing implant materials by exploring the use of advanced materials known as Bulk Metallic Glasses (BMGs) and their composites for knee implants. BMGs offer unique properties such as high strength, elasticity, corrosion resistance, and biocompatibility, making them attractive for biomedical applications. However, there are challenges associated with the development of Zr-based BMGs specifically for knee implants, including size limitations, brittle behaviour, and long-term biosafety concerns. The proposed research aims to overcome these challenges through various approaches, including the addition of suitable elements, partial crystallization of amorphous materials, and the use of new manufacturing techniques like Selective Laser Melting (SLM). The scientific objectives of this proposal are to assess the fabrication of metallic glass knee implants using SLM, investigate their mechanical properties, corrosion, and tribocorrosion behaviour, and evaluate their potential as durable and cost-effective load-bearing implants. The research also focuses on developing Ni-free Zr-Nb-Al-Ti-(Cu/Ag) and Zr-Nb-Al-Fe-(Cu/Ag) metallic glasses with enhanced biocompatibility and wear resistance, aiming to reduce revision surgeries. The proposed methodology involves selecting suitable alloy systems, producing amorphous powders through gas atomization, performing SLM experiments to fabricate BMGs, and characterizing the samples using various techniques such as X-ray diffraction, electron microscopy, and thermal analysis. The biocompatibility, corrosion resistance, wear resistance, and mechanical behaviour of the fabricated BMGs will be extensively studied. This methodology is based on the existing knowledge in biomaterials and additive manufacturing and is expected to contribute to the development of high-quality metal glass knee implants. Overall, this research proposal aims to address the limitations of current knee implants by exploring the use of novel Selective Laser Melted Bulk Metallic Glasses. The findings from this study have the potential to significantly improve the quality and longevity of knee implants, benefiting millions of people suffering from knee-related issues worldwide.

Research institution(s)
  • Österreichische Akademie der Wissenschaften - 100%
Project participants
  • Jürgen Eckert, Montanuniversität Leoben , mentor

Research Output

  • 4 Publications
  • 1 Methods & Materials
  • 1 Disseminations
Publications
  • 2024
    Title In-vitro corrosion and tribocorrosionbehaviour of highly adherent ZrO2ceramic coating for load-bearing implants
    Type Conference Proceeding Abstract
    Author Ramasamy P
    Conference Materials Science and Engineering MSE Congress 2024
    Link Publication
  • 2025
    Title Development of Biocompatible Toxic-free elements Zr-Based Bulk Metallic Glasses for Biomedical Applications
    Type Conference Proceeding Abstract
    Author Ramasamy P
    Conference THERMEC 2025 International Conference on PROCESSING & MANUFACTURING OF ADVANCED MATERIALS Processing, Fabrication, Properties, Applications
    Link Publication
  • 2025
    Title High Corrosion Resistance and Biocompatible Zr-Based Bulk Metallic Glasses for Load-Bearing Implants
    Type Conference Proceeding Abstract
    Author Ramasamy P
    Conference 29th International Symposium on Metastable, Amorphous, and Nanostructured Materials ISMANAM 2025
    Link Publication
  • 0
    Title Structure-Property-Bioresponse Correlation in Zr-Based Metallic Glasses: From GFA to Corrosion Resistance and Gene Expression
    Type Journal Article
    Author Ramasamy P
    Journal Advanced Functional Materials
Methods & Materials
  • 2024
    Title Inflammatory response evaluation
    Type Biological samples
    Public Access
Disseminations
  • 2025
    Title Seminar Lecture on Bulk Metallic Glasses
    Type A formal working group, expert panel or dialogue

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+43 1 505 67 40

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