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Pro-Active Routing for Emergency Testing in Pandemics

Jan Fabian Ehmke (ORCID: 0000-0001-8474-7483)
  • Grant DOI 10.55776/I5908
  • Funding program Principal Investigator Projects International
  • Status Ended
  • Start October 1, 2022
  • End April 30, 2026
  • Funding amount € 387,182

Weave

Disciplines

Computer Sciences (30%); Economics (70%)

Keywords

  • Routing,
  • Reinforcement Learning,
  • Simulation,
  • Disease Spreading,
  • Logistics
Abstract Final report

In the COVID-19 pandemic, we saw that rapid and efficient testing can effectively slow the spread of a virus. However, especially at the beginning of the pandemic, testing was extraordinarily time- consuming and expensive, and testing resources were not available everywhere on the scale required. Authorities responded to this challenge with innovative ideas: in Vienna, for example, a bicycle-based team of mobile testers was created, which could be requested in case of suspicion. The mobile tester fleet could then collect samples from suspected cases, bring them for evaluation, and thus help reduce further spread. Based on the idea of a mobile fleet of testers, we now want to investigate in this research project how scarce resources can be used sensibly in a dynamic environment by planning ahead. For this purpose, modern methods and tools from agent-based simulation, data analysis and dynamic vehicle routing are used. For the COVID-19 example, this means, for example, not waiting for potential suspicious cases, but using simulation to predict how a pandemic will spread, so that suitable tests can then be carried out in advance. This first requires a forecast by means of a spread model, which is already available for the COVID-19 example due to the extensive data situation. But at which point should one test already in advance? The underlying problem must be mathematically formulated and analyzed for this purpose. In addition to agent-based simulation, innovative learning methods are also used to ensure that the test resources are used as effectively as possible. This then results in a catalog of policies that are examined in the simulation for their effectiveness. For what kind of problems is such an approach useful at all? Which policies of predictive planning work particularly well? Abstracting from the COVID-19 example, we also want to analyze similar problems. When is the interaction of predictive planning in combination with machine learning helpful? How can detailed simulations improve forecasts? And how does one computationally feasibly integrate information from highly complex simulations into predictive planning? Examples here extend far beyond COVID- 19, e.g., to demand forecasting for delivery services. Participants in the project are Univ.-Prof. Jan Fabian Ehmke from the University of Vienna, who will focus on demand modeling. In addition, there is the expertise of Univ.-Prof. Dr. Marlin Ulmer, University of Magdeburg, who will be responsible for learning procedures related to predictive vehicle routing. Evaluation and demand generation will be done by Dr. Niki Popper (TU Wien), who is an expert in the area of agent-based simulation.

We live in a world full of dynamic and heterogeneous socio-economical and socio-ecological challenges. In the project "Pro-Active Routing for Emergency Testing in Pandemics", we addressed these challenges with simulation-based analytics (SimBA). From a methodology perspective, SimBA entailed data-driven, smart decision making including causal and expert information. The starting point was data on pandemic dispersal, which could be derived from large databases. In addition, simulation of socio-economical relationships and systems provided synthetic data on pandemic spread. Our simulation focused on microscopic, agent-based models. The data and information created were transformed into information models, which described complex socio-economical relationships compactly. This information was considered in anticipatory decision models, which allow for making smart resource allocation decisions. The impact of these decisions was evaluated by simulation models again. In particular, in several papers and in a joint review paper, we focused on descriptive, predictive and prescriptive analytics for resource allocation in pandemic management. As the COVID-19 pandemic demonstrated, having the right containment resources, such as testing kits, vaccines, and personal protective equipment like masks, at the right time and location to achieve effective pandemic containment and to mitigate pandemic spread is both critical and challenging. High-quality predictions are essential for allocating such scarce resources, and substantial work has been conducted on descriptive and predictive analytics during the COVID-19 pandemic. Policymakers attempted to incorporate the resulting information into immediate decision making in reaction to the predicted spread. However, to be prepared for the next pandemic, we worked on prescriptive analytics models that account for the dynamic interaction between predicted pandemic development and prescribed resource allocation. This integrated view has been limited in the literature, and we tried to contribute with this project by closing this gap. To this end, we provided several papers on analytics research conducted on the case of the COVID-19 pandemic and its impact on resource allocation. We developed dynamic and stochastic resource allocation models that consider historical data of pandemics spread and optimized resource allocation as needed. Data from simulation and the COVID-19 pandemic were included in extended optimization models and can help to assign the right containment resources where needed in the future.

Research institution(s)
  • Universität Wien - 61%
  • Technische Universität Wien - 39%
Project participants
  • Nikolas Popper, Technische Universität Wien , associated research partner
International project participants
  • Marlin Ulmer, Otto-von-Guericke-Universität Magdeburg - Germany, project partner
  • Warren Powell, Princeton University - USA
  • Ann Melissa Campbell, University of Iowa - USA

Research Output

  • 178 Citations
  • 19 Publications
  • 1 Scientific Awards
Publications
  • 2026
    Title Novel concepts for agent-based population modelling and simulation: GEPOC ABM 2025
    DOI 10.1016/j.simpat.2026.103339
    Type Journal Article
    Author Bicher M
    Journal Simulation Modelling Practice and Theory
  • 2025
    Title Simulation-based genetic algorithm for optimizing a municipal cooperative waste supply chain in a pandemic
    DOI 10.1016/j.engappai.2024.109478
    Type Journal Article
    Author Ghasemi P
    Journal Engineering Applications of Artificial Intelligence
    Pages 109478
    Link Publication
  • 2026
    Title Analytics for Resource Allocation in Pandemic Management
    DOI 10.1287/inte.2025.0275
    Type Journal Article
    Author Haferkamp J
    Journal INFORMS Journal on Applied Analytics
  • 2024
    Title Supply chain network design based on Big Data Analytics: heuristic-simulation method in a pharmaceutical case study
    DOI 10.1080/09537287.2024.2344729
    Type Journal Article
    Author Goodarzian F
    Journal Production Planning & Control
    Pages 1-21
    Link Publication
  • 2025
    Title Managing equitable contagious disease testing: A mathematical model for resource optimization
    DOI 10.1016/j.omega.2025.103305
    Type Journal Article
    Author Ghasemi P
    Journal Omega
  • 2023
    Title Four Years of Not-Using a Simulator: The Agent-Based Template
    DOI 10.1109/wsc60868.2023.10408482
    Type Conference Proceeding Abstract
    Author Brunmeir D
    Pages 255-266
  • 2025
    Title A Cost Function Approximation Based Large Neighborhood Search for Dynamic Medical Courier Services
    DOI 10.1002/net.70009
    Type Journal Article
    Author Haferkamp J
    Journal Networks
    Pages 47-61
    Link Publication
  • 2022
    Title Evaluating the efficiency of relief centers in disaster and epidemic conditions using multi-criteria decision-making methods and GIS: A case study
    DOI 10.1016/j.ijdrr.2022.103512
    Type Journal Article
    Author Choukolaei H
    Journal International Journal of Disaster Risk Reduction
    Pages 103512
    Link Publication
  • 2023
    Title A DEA-based simulation-optimisation approach to design a resilience plasma supply chain network: a case study of the COVID-19 outbreak
    DOI 10.1080/23302674.2023.2224105
    Type Journal Article
    Author Ghasemi P
    Journal International Journal of Systems Science: Operations & Logistics
    Pages 2224105
  • 2023
    Title A state-of-the-art review of operation research models and applications in home healthcare
    DOI 10.1016/j.health.2023.100228
    Type Journal Article
    Author Goodarzian F
    Journal Healthcare Analytics
  • 2025
    Title Model-Based Optimisation of Outbreak Detection via Wastewater Probing
    Type Conference Proceeding Abstract
    Author Bicher M
    Conference 11th Vienna International Conference on Mathematical Modelling
    Pages 9-10
    Link Publication
  • 2025
    Title Novel Concepts for Agent-Based Population Modelling and Simulation: Updates from GEPOC ABM
    DOI 10.48550/arxiv.2511.05637
    Type Preprint
    Author Bicher M
    Link Publication
  • 2025
    Title GEPOC Parameters -- Open Source Parametrisation and Validation for Austria, Version 2.0
    DOI 10.48550/arxiv.2511.00048
    Type Preprint
    Author Bicher M
    Link Publication
  • 2025
    Title GEPOC ABM, Generic Population Concept -- Agent-Based Model, Version 2.2
    DOI 10.48550/arxiv.2510.20840
    Type Preprint
    Author Bicher M
    Link Publication
  • 2025
    Title A case-driven simulation-optimization model for sustainable medical logistics network
    DOI 10.1016/j.seps.2025.102271
    Type Journal Article
    Author Goodarzian F
    Journal Socio-Economic Planning Sciences
    Pages 102271
    Link Publication
  • 2024
    Title Designing green logistics networks under carbon tax policy: Post-COVID condition
    DOI 10.1016/j.rineng.2024.102830
    Type Journal Article
    Author Abbasi S
    Journal Results in Engineering
    Pages 102830
    Link Publication
  • 2024
    Title Optimizing urban bike-sharing systems: a stochastic mathematical model for infrastructure planning
    DOI 10.1007/s10100-024-00950-z
    Type Journal Article
    Author Ahmadi S
    Journal Central European Journal of Operations Research
    Pages 125-159
    Link Publication
  • 2024
    Title Modeling of Agent Decisions Using Conditional Generative Adversarial Networks
    DOI 10.1109/wsc63780.2024.10838996
    Type Conference Proceeding Abstract
    Author Bicher M
    Pages 2643-2654
  • 2023
    Title A fuzzy sustainable model for COVID-19 medical waste supply chain network
    DOI 10.1007/s10700-023-09412-8
    Type Journal Article
    Author Goodarzian F
    Journal Fuzzy Optimization and Decision Making
    Pages 93-127
    Link Publication
Scientific Awards
  • 2024
    Title Dissertation Award
    Type Research prize
    Level of Recognition National (any country)

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