Research area: Molecular Biology, Genetics, Microbiology

Place: BOKU University – Tulln, Austria

Department of Agricultural Sciences, Institute of Microbial Genetics (IMiG)

A Master’s thesis position is available in the Fungal Bioactive Metabolites and Systems Biology Group at BOKU University (Campus Tulln). The thesis will be embedded in an ongoing research project focusing on the genetic and functional analysis of mycoparasitic and plant-associated fungi.

The project centers on the development and application of CRISPR/Cas-based genome editing in mycoparasitic fungi, with a particular focus on targeted modification of genes encoding Lytic Polysaccharide Monooxygenases (LPMOs).

LPMOs are emerging as multifunctional proteins with potential roles beyond polysaccharide degradation, including involvement in microbial interactions.

Thesis focus

• Development and optimization of CRISPR/Cas-based genome editing tools in mycoparasitic fungi

• Targeted genetic modification of LPMO-encoding genes (e.g. gene disruption or tagging)

• Basic characterization of edited fungal strains

The exact scope of the project will be adapted to the student’s background and the duration of the thesis.

Candidate profile

• Enrollment in a Master’s program in Molecular Biology, Biotechnology, Microbiology, or a related field

• Strong interest in fungal biology, enzyme function, and microbial interactions

• Basic experience in molecular biology techniques (e.g. cloning, PCR, etc.)

• Good English communication skills and motivation to work independently

We offer

• A well-defined Master’s thesis project embedded in an active research environment

• Hands-on training in fungal genetics and CRISPR/Cas technologies

• Close supervision within an international research team

• Access to modern laboratory infrastructure at the BOKU Campus Tulln

• Small financial support to assist with commuting costs during the thesis

Application

Interested students are invited to contact:

Dr. Lea Atanasova

Institute of Microbial Genetics (IMiG), BOKU University; lea.atanasova(at)boku.ac.at

 

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