• Skip to content (access key 1)
  • Skip to search (access key 7)
FWF — Austrian Science Fund
  • Go to overview page Discover

    • Research Radar
      • Research Radar Archives 1974–1994
    • Discoveries
      • Emmanuelle Charpentier
      • Adrian Constantin
      • Monika Henzinger
      • Ferenc Krausz
      • Wolfgang Lutz
      • Walter Pohl
      • Christa Schleper
      • Anton Zeilinger
    • Impact Stories
      • Verena Gassner
      • Wolfgang Lechner
      • Georg Winter
    • scilog Magazine
    • Austrian Science Awards
      • FWF Wittgenstein Awards
      • FWF ASTRA Awards
      • FWF START Awards
      • Award Ceremony
    • excellent=austria
      • Clusters of Excellence
      • Emerging Fields
    • In the Spotlight
      • 40 Years of Erwin Schrödinger Fellowships
      • Quantum Austria
    • Dialogs and Talks
      • think.beyond Summit
    • E-Book Library
  • Go to overview page Funding

    • Portfolio
      • excellent=austria
        • Clusters of Excellence
        • Emerging Fields
      • Projects
        • Principal Investigator Projects
        • Principal Investigator Projects International
        • Clinical Research
        • 1000 Ideas
        • Arts-Based Research
        • FWF Wittgenstein Award
      • Careers
        • ESPRIT
        • FWF ASTRA Awards
        • Erwin Schrödinger
        • doc.funds
        • doc.funds.connect
      • Collaborations
        • Specialized Research Groups
        • Special Research Areas
        • Research Groups
        • International – Multilateral Initiatives
        • #ConnectingMinds
      • Communication
        • Top Citizen Science
        • Science Communication
        • Book Publications
        • Digital Publications
        • Open-Access Block Grant
      • Subject-Specific Funding
        • AI Mission Austria
        • Belmont Forum
        • ERA-NET HERA
        • ERA-NET NORFACE
        • ERA-NET QuantERA
        • ERA-NET TRANSCAN
        • Alternative Methods to Animal Testing
        • European Partnership Biodiversa+
        • European Partnership ERA4Health
        • European Partnership ERDERA
        • European Partnership EUPAHW
        • European Partnership FutureFoodS
        • European Partnership OHAMR
        • European Partnership PerMed
        • European Partnership Water4All
        • Gottfried and Vera Weiss Award
        • netidee SCIENCE
        • Herzfelder Foundation Projects
        • Quantum Austria
        • Rückenwind Funding Bonus
        • WE&ME Award
        • Zero Emissions Award
      • International Collaborations
        • Belgium/Flanders
        • Germany
        • France
        • Italy/South Tyrol
        • Japan
        • Luxembourg
        • Poland
        • Switzerland
        • Slovenia
        • Taiwan
        • Tyrol–South Tyrol–Trentino
        • Czech Republic
        • Hungary
    • Step by Step
      • Find Funding
      • Submitting Your Application
      • International Peer Review
      • Funding Decisions
      • Carrying out Your Project
      • Closing Your Project
      • Further Information
        • Integrity and Ethics
        • Inclusion
        • Applying from Abroad
        • Personnel Costs
        • PROFI
        • Final Project Reports
        • Final Project Report Survey
    • FAQ
      • Project Phase PROFI
        • Accounting for Approved Funds
        • Labor and Social Law
        • Project Management
      • Project Phase Ad Personam
        • Accounting for Approved Funds
        • Labor and Social Law
        • Project Management
      • Expiring Programs
        • Elise Richter and Elise Richter PEEK
        • FWF START Awards
  • Go to overview page About Us

    • Mission Statement
    • FWF Video
    • Values
    • Facts and Figures
    • Annual Report
    • What We Do
      • Research Funding
        • Matching Funds Initiative
      • International Collaborations
      • Studies and Publications
      • Equal Opportunities and Diversity
        • Objectives and Principles
        • Measures
        • Creating Awareness of Bias in the Review Process
        • Terms and Definitions
        • Your Career in Cutting-Edge Research
      • Open Science
        • Open-Access Policy
          • Open-Access Policy for Peer-Reviewed Publications
          • Open-Access Policy for Peer-Reviewed Book Publications
          • Open-Access Policy for Research Data
        • Research Data Management
        • Citizen Science
        • Open Science Infrastructures
        • Open Science Funding
      • Evaluations and Quality Assurance
      • Academic Integrity
      • Science Communication
      • Philanthropy
      • Sustainability
    • History
    • Legal Basis
    • Organization
      • Executive Bodies
        • Executive Board
        • Supervisory Board
        • Assembly of Delegates
        • Scientific Board
        • Juries
      • FWF Office
    • Jobs at FWF
  • Go to overview page News

    • News
    • Press
      • Logos
    • Calendar
      • Post an Event
      • FWF Informational Events
    • Job Openings
      • Enter Job Opening
    • Newsletter
  • Discovering
    what
    matters.

    FWF-Newsletter Press-Newsletter Calendar-Newsletter Job-Newsletter scilog-Newsletter

    SOCIAL MEDIA

    • LinkedIn, external URL, opens in a new window
    • , external URL, opens in a new window
    • Facebook, external URL, opens in a new window
    • Instagram, external URL, opens in a new window
    • YouTube, external URL, opens in a new window

    SCILOG

    • Scilog — The science magazine of the Austrian Science Fund (FWF)
  • elane login, external URL, opens in a new window
  • Scilog external URL, opens in a new window
  • de Wechsle zu Deutsch

  

MUW International PhD Program in Translational Oncology (IPPTO)

MUW International PhD Program in Translational Oncology (IPPTO)

Gergely Szakacs (ORCID: 0000-0002-9311-7827)
  • Grant DOI 10.55776/DOC59
  • Funding program doc.funds
  • Status ended
  • Start October 1, 2019
  • End September 30, 2024
  • Funding amount € 1,902,624
  • Project website
  • dc

Disciplines

Clinical Medicine (25%); Medical-Theoretical Sciences, Pharmacy (75%)

Keywords

    Novel Cancer Therapies, Cancer Immunotherapy, Therapy Resistance, Mouse Models, Cancer Immunology, Non-Genetic Cancer Cell Plasticity

Abstract Final report

The unprecedented understanding of the molecular underpinning of cancer has led to an explosion of targeted therapy options that are developed at a rapid pace. Cancer immunotherapy, genome editing and rational drug design are just a few of the novel ideas that will massively change how we target cancer therapeutically. However, there are numerous challenges that need to be overcome before delivering on the promise of personalized cancer therapy. Clinical evidence shows that, despite initial response to treatment, most tumors become resistant to eventually all available therapy by alterations of the malignant cells or the tumor microenvironment. In recognition of this challenge, we propose to establish a new research focus dedicated to mechanisms shaping anticancer therapy response. With a significant in-kind contribution from the Medical University of Vienna (MUW) matching the FWF DOC funds, our aim is to improve the already existing and highly successful Malignant Diseases doctoral program (MADI), which is one of the largest and best-established thematic PhD programs of the MUW. The novel International PhD Program in Translational Oncology (IPPTO) is a closed excellence program run by 14 MUW scientists of the MADI faculty with a wide range of expertise and research interests. One-third of the faculty members are women, including a highly successful female young group leader, reflecting our vision to support and embrace early-career scientists who have the potential to serve as academic role models in research and education. The proposed IPPTO projects belong to three research areas, focusing on cellular resistance mechanisms, tumor plasticity and the tumor microenvironment. The success of this three- pronged approach is hinged on the excellence and commitment of the faculty members to train future scientists through innovative and exciting research. Students will benefit from the thematic coherence of the projects, the collaboration network of the faculty members, the interdisciplinary approach, the shared resources and a team-level supervision. The program will include customized training courses, seminars and regular participation in national and international meetings. Our long-term goal is to create an internationally visible excellence program in translational oncology. An increase of the quality of graduate training and career development in oncology will strengthen the research cluster Cancer Research and Oncology at MUW and the entire Austrian cancer research potential to promote the translation of basic scientific discoveries into clinical benefit for cancer patients.

The international PhD program "Translational Oncology" (IPPTO) at the Institute of Cancer Research at MedUni Vienna was built on the collaboration of fourteen scientists with diverse yet complementary expertise in oncology research. The program focused on three key research areas: cellular resistance factors, tumor plasticity, and the tumor microenvironment. Through this initiative, the well-established thematic PhD program "Malignant Diseases (MADI)" at MedUni Vienna was further refined and strengthened. IPPTO students benefited from the program's thematic cohesion, the faculty's extensive collaboration network, an interdisciplinary approach, enhanced access to resources, and team-based supervision. The dedication of the participating scientists to training highly qualified researchers formed the program's foundation-complemented by personalized training opportunities and active participation in national and international meetings and conferences. In the long run, the IPPTO program contributed to advancing cancer research in Austria and facilitating the translation of scientific discoveries into improved treatment strategies for cancer patients.

Consortium
  • Christine Brostjan, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
  • Dietmar Herndler-Brandstetter, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
  • Emilio Manuel Casanova Hevia, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
  • Gerda Egger, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
  • Gergely Szakacs, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
  • Lukas Kenner, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
  • Maria Sibilia, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
  • Paola Martinelli, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
  • Peter Valent, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
  • Petra Heffeter, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
  • Robert Eferl, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
  • Stephan N. Wagner, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
  • Walter Berger, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
  • Wolfgang Mikulits, Medizinische Universität Wien
    consortium member (01.10.2019 - 30.09.2024)
Research institution(s)
  • Medizinische Universität Wien

Research Output

  • 714 Citations
  • 66 Publications
  • 1 Spinouts
  • 5 Policies
  • 2 Methods & Materials
  • 6 Disseminations
  • 27 Scientific Awards
  • 18 Fundings

Discovering
what
matters.

Newsletter

FWF-Newsletter Press-Newsletter Calendar-Newsletter Job-Newsletter scilog-Newsletter

Contact

Austrian Science Fund (FWF)
Georg-Coch-Platz 2
(Entrance Wiesingerstraße 4)
1010 Vienna

office(at)fwf.ac.at
+43 1 505 67 40

General information

  • Job Openings
  • Jobs at FWF
  • Press
  • Philanthropy
  • scilog
  • FWF Office
  • Social Media Directory
  • LinkedIn, external URL, opens in a new window
  • , external URL, opens in a new window
  • Facebook, external URL, opens in a new window
  • Instagram, external URL, opens in a new window
  • YouTube, external URL, opens in a new window
  • Cookies
  • Whistleblowing/Complaints Management
  • Accessibility Statement
  • Data Protection
  • Acknowledgements
  • Social Media Directory
  • © Österreichischer Wissenschaftsfonds FWF
© Österreichischer Wissenschaftsfonds FWF