Characterization of the Intracellular Degradation of Methotrexate Polyglutamates in Blasts from Childhood Acute Lymphoblastic Leukemia

Leo Kager (ORCID: 0000-0003-4954-6488)

Disciplines

Clinical Medicine (50%); Medical-Theoretical Sciences, Pharmacy (50%)

Keywords

  • METHOTREXATE,
  • ACUTE LYMPHOBLASTIC LEUKEMIA,
  • PLOIDY AND LINEAGE DIFFERENCES,
  • GAMMA-GLUTAMYL-HYDROLASE,
  • CHILDHOOD,
  • INTRACELLULAR METABOLISM
Research institution: abroad phase

Research Output

  • 141 Citations
  • 1 Publications
Publications
  • 2005
    Title Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics
    DOI 10.1172/jci22477
    Type Journal Article
    Author Kager L
    Journal Journal of Clinical Investigation
    Pages 110-117
    Link Publication