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RNA Biology

RNA Biology

Andrea Barta (ORCID: 0000-0002-8851-406X)
  • Grant DOI 10.55776/W1207
  • Funding program Doctoral Programs
  • Status ended
  • Start June 1, 2007
  • End November 30, 2021
  • Funding amount € 9,034,512
  • Project website

Disciplines

Biology (65%); Medical-Theoretical Sciences, Pharmacy (35%)

Keywords

    Alternative Splicing, RNA editing, RNA localization, Mirna And Sirna In Translational Control, Non-protein coding RNA, Epigenetic gene silencing

Abstract

A focussed doctoral program on "RNA Biology" is planned within the framework of the "International PhD Program on Molecular Life Sciences at the Vienna Biocenter" which is a joint program from the Max F. Perutz Laboratories (Medical University Vienna and University Vienna), the Institute of Molecular Pathology (IMP) and two institutes form the Austrian Academy of Sciences (CeMM and IMBA). Research groups from all these institutions participate in this doctoral program ensuring an excellent coverage of research topics in the field of RNA Biology. The applying faculty participates in several national and international program projects and networks. This will support the PhD students in their research projects and career development as well as bestow them with a broad visibility. This PhD program will offer projects in many aspects of this exciting research field ranging from the problem how proper RNA folding is achieved in nature, how RNA is localized in specialized cells, how the diverse proteome of higher eukaryotes is established by alternative splicing and RNA editing, how small non-coding RNAs exert their function in regulating gene expression and genome stability and how long non-coding RNA are able to silence gene loci and whole chromosomes. The close collaboration of the research groups together with the multidisciplinary setting of the Vienna Biocenter PhD program will be of great benefit for the PhD students, for their scientific education as well as for their future careers.

Consortium
  • Andrea Barta, Medizinische Universität Wien
    consortium member (01.06.2007 - 30.11.2021)
  • Arndt Von Haeseler, Universität Wien
    consortium member (01.06.2007 - 30.11.2021)
  • Isabella Moll, Universität Wien
    consortium member (01.06.2007 - 30.11.2021)
  • Ivo Ludwig Hofacker, Universität Wien
    consortium member (01.06.2007 - 30.11.2021)
  • Javier Martinez Fernandez, Medizinische Universität Wien
    consortium member (01.06.2007 - 30.11.2021)
  • Maria Luisa Cochella, Institut für Molekulare Pathologie - IMP
    consortium member (01.06.2007 - 30.11.2021)
  • Michael F. Jantsch, Universität Wien
    consortium member (01.06.2007 - 30.11.2021)
  • Stefan L. Ameres, Österreichische Akademie der Wissenschaften
    consortium member (01.06.2007 - 30.11.2021)
  • Udo Bläsi, Universität Wien
    consortium member (01.06.2007 - 30.11.2021)
  • Walter Rossmanith, Medizinische Universität Wien
    consortium member (01.06.2007 - 30.11.2021)
Research institution(s)
  • Universität Wien
  • Universität Wien
  • Universität Wien
  • Universität Wien
  • IMBA – Institut für Molekulare Biotechnologie GmbH
  • Gregor Mendel Institute of Molecular Plant Biology
  • Institut für Molekulare Pathologie - IMP
  • Medizinische Universität Wien
  • Medizinische Universität Wien
Project participants
  • Michael D. Nodine, Gregor Mendel Institute of Molecular Plant Biology , associated research partner
  • Boris Görke, Universität Wien , associated research partner
  • Alexander Stark, Institut für Molekulare Pathologie - IMP , associated research partner
  • Julius Brennecke, IMBA – Institut für Molekulare Biotechnologie GmbH , associated research partner

Research Output

  • 60875 Citations
  • 347 Publications
Publications
  • 2022
    Title Quantifying heterologous gene expression during ectopic MazF production in Escherichia coli
    DOI 10.1186/s13104-022-06061-9
    Type Journal Article
    Author Nikolic N
    Journal BMC Research Notes
    Pages 173
    Link Publication
  • 2022
    Title Rewiring of Gene Expression in Pseudomonas aeruginosa During Diauxic Growth Reveals an Indirect Regulation of the MexGHI-OpmD Efflux Pump by Hfq
    DOI 10.3389/fmicb.2022.919539
    Type Journal Article
    Author Rozner M
    Journal Frontiers in Microbiology
    Pages 919539
    Link Publication
  • 2022
    Title The Drosophila ZAD zinc finger protein Kipferl guides Rhino to piRNA clusters
    DOI 10.7554/elife.80067
    Type Journal Article
    Author Baumgartner L
    Journal eLife
    Link Publication
  • 2022
    Title Insights into the secondary and tertiary structure of the Bovine Viral Diarrhea Virus Internal Ribosome Entry Site
    DOI 10.1080/15476286.2022.2058818
    Type Journal Article
    Author Gosavi D
    Journal RNA Biology
    Pages 496-506
    Link Publication
  • 2022
    Title Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery
    DOI 10.1038/s41594-022-00721-x
    Type Journal Article
    Author Andreev V
    Journal Nature Structural & Molecular Biology
    Pages 130-142
  • 2022
    Title Assembly principle of a membrane-anchored nuclear pore basket scaffold
    DOI 10.1126/sciadv.abl6863
    Type Journal Article
    Author Cibulka J
    Journal Science Advances
    Link Publication
  • 2021
    Title A genetic toolkit for studying transposon control in the Drosophila melanogaster ovary
    DOI 10.1101/2021.06.29.450424
    Type Preprint
    Author Elmaghraby M
    Pages 2021.06.29.450424
    Link Publication
  • 2021
    Title A SUMO-dependent regulatory switch connects the piRNA pathway to the heterochromatin machinery in Drosophila
    DOI 10.1101/2021.07.27.453956
    Type Preprint
    Author Andreev V
    Pages 2021.07.27.453956
    Link Publication
  • 2021
    Title Stabilization of Hfq-mediated translational repression by the co-repressor Crc in Pseudomonas aeruginosa
    DOI 10.1093/nar/gkab510
    Type Journal Article
    Author Malecka E
    Journal Nucleic Acids Research
    Pages 7075-7087
    Link Publication
  • 2021
    Title A genetic toolkit for studying transposon control in the Drosophila melanogaster ovary
    DOI 10.1093/genetics/iyab179
    Type Journal Article
    Author Elmaghraby M
    Journal Genetics
    Link Publication
  • 2021
    Title Light regulates alternative splicing outcomes via the TOR kinase pathway
    DOI 10.1016/j.celrep.2021.109676
    Type Journal Article
    Author Riegler S
    Journal Cell Reports
    Pages 109676
    Link Publication
  • 2021
    Title Specific and Global RNA Regulators in Pseudomonas aeruginosa
    DOI 10.3390/ijms22168632
    Type Journal Article
    Author Pusic P
    Journal International Journal of Molecular Sciences
    Pages 8632
    Link Publication
  • 2021
    Title Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex
    DOI 10.1101/gad.347989.120
    Type Journal Article
    Author Schnabl J
    Journal Genes & Development
    Pages 392-409
    Link Publication
  • 2021
    Title Gene Expression Profiling of Pseudomonas aeruginosa Upon Exposure to Colistin and Tobramycin
    DOI 10.3389/fmicb.2021.626715
    Type Journal Article
    Author Sesso A
    Journal Frontiers in Microbiology
    Pages 626715
    Link Publication

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