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Metabolic and Cardiovascular Disease

Metabolic and Cardiovascular Disease

Gerald Höfler (ORCID: 0000-0002-9056-3063)
  • Grant DOI 10.55776/W1226
  • Funding program Doctoral Programs
  • Status ended
  • Start July 1, 2010
  • End June 30, 2024
  • Funding amount € 9,922,437
  • Project website
  • dc

Disciplines

Biology (60%); Medical-Theoretical Sciences, Pharmacy (40%)

Keywords

    Lipid-Associated Disorders, Mouse And Cell Culture Models, Gene And Protein Regulation, Channel Function And Cation Handling, Cardiovascular Disease, Molecular Pathology

Abstract

The doctoral program "Metabolic and Cardiovascular Disease" (DK-MCD) is an educational program hosted by the Medical University of Graz, Austria. Fifteen researchers from three universities (Medical University of Graz, University of Graz, Graz University of Technology) have developed a multidisciplinary graduate training program to investigate the molecular mechanisms and cellular functions involved in the pathogenesis of metabolic and cardiovascular disease. The thematic diversity of the DK-MCD ensures broad exposure of the participating students to important issues in biomedicine. Research topics were selected to maximize exchange within the consortium concerning technical proficiency and advances in biomedical research. Importantly, the DK-MCD is sufficiently diverse to encourage students to look beyond the focus of their own research. To provide a stimulating and provocative research environment, the DK-MCD faculty was chosen for their excellence in research as indicated by publishing and funding records as well as their excellence in teaching. The faculty represents a well-balanced combination of established and junior scientists. Especially in the latter group female researchers have a prominent role. All DK-MCD faculty members are involved in local, national and international research networks. Thus, the DK-MCD will be embedded in an established inter-laboratory cooperation and communication environment. Faculty members contribute to this initiative by their scientific background in both basic research and clinical medicine. Their technical expertise is complemented by excellent infrastructure and state-of-the-art technology for biomedical research. The DK-MCD faculty is well experienced in training doctoral students. The biomedically-oriented DK-MCD curriculum complements the existing biotechnology-oriented DK-Plus "Molecular Enzymology". Therefore, our initiative fills an existing gap and covers essential educational aspects for life sciences not yet available in Graz. The DK-MCD provides a challenging PhD education program which is unique because it (i) comprises a multidisciplinary faculty from three local universities, (ii) requires (inter)national student exchange and (iii) covers major topics in metabolic and cardiovascular disease from basic research to clinical aspects in a translational approach. We are confident that the DK-MCD will attract highly motivated and dedicated students seeking knowledge and skills that will enable them to pursue careers in areas of growing importance for health and society.

Consortium
  • Dagmar Kratky, Medizinische Universität Graz
    consortium member (01.07.2010 - 30.06.2024)
  • Frank Madeo, Universität Graz
    consortium member (01.07.2010 - 30.06.2024)
  • Gerald Höfler, Medizinische Universität Graz
    consortium member (01.07.2010 - 30.06.2024)
  • Günter Hämmerle, Universität Graz
    consortium member (01.07.2010 - 30.06.2024)
  • Klaus Groschner, Medizinische Universität Graz
    consortium member (01.07.2010 - 30.06.2024)
  • Martin Pichler, Medizinische Universität Graz
    consortium member (01.07.2010 - 30.06.2024)
  • Peter Fickert, Medizinische Universität Graz
    consortium member (01.07.2010 - 30.06.2024)
  • Ruth Birner-Grünberger, Technische Universität Wien
    consortium member (01.07.2010 - 30.06.2024)
  • Tobias Madl, Medizinische Universität Graz
    consortium member (01.07.2010 - 30.06.2024)
  • Wolfgang F. Graier, Medizinische Universität Graz
    consortium member (01.07.2010 - 30.06.2024)
Research institution(s)
  • Universität Graz
  • Medizinische Universität Graz
Project participants
  • Ronald Philip Kühnlein, Universität Graz , national collaboration partner
International project participants
  • Kerry-Anne Rye, University of New South Wales - Australia
  • Jason R. B. Dyck, University of Alberta - Canada
  • Jasminka Stefulj, Rudjer Boskovic Institute - Croatia
  • Leos Shivaya Valasek, Academy of Sciences of the Czech Republic - Czechia
  • Karsten Kristiansen, University of Copenhagen - Denmark
  • Matti Jauhiainen, Minerva Institute for Medical Research - Finland
  • Eric Honore, Centre National de la Recherche Scientifique - France
  • Sylvain Richard, Centre National de la Recherche Scientifique Montpellier - France
  • Guido Kroemer, INSERM U1138 - France
  • Jérôme Galon, Institut National de la Santé et de la Recherche Médicale - France
  • Wolfgang Linke, Westfälische Wilhelms-Universität - Germany
  • Stephan E. Lehnart, Universitätsmedizin Göttingen - Germany
  • Pavel Strnad, Universitätsklinikum Ulm - Germany
  • Klaus Pantel, Universitätsklinikum Hamburg-Eppendorf - Germany
  • Jörg Heeren, Universitätsklinikum Hamburg-Eppendorf - Germany
  • Alexandra K. Kiemer, Universität des Saarlandes - Germany
  • Christian Pott, Universität Münster - Germany
  • Jürgen Arnhold, Universität Leipzig - Germany
  • Elke Deuerling, Universität Konstanz - Germany
  • Stephan Baldus, Uniklinik Köln - Germany
  • Lars Maier, Universitätsmedizin Göttingen - Germany
  • Friedrich Lottspeich, Max-Planck-Gesellschaft - Germany
  • Hans R. Lehrach, Max Planck-Institut - Germany
  • Thomas Gudermann, Ludwig-Maximilians-Universität München - Germany
  • Thomas Cremer, Ludwig-Maximilians-Universität München - Germany
  • Karl Lenhard Rudolph, Leibniz Gemeinschaft - Germany
  • Gerd Hasenfuß, Georg-August-Universität Göttingen - Germany
  • Regine Heller, Friedrich Schiller Universität Jena - Germany
  • Markus Hecker, Ruprecht-Karls-Universität Heidelberg - Germany
  • Stephan Sigrist, Freie Universität Berlin - Germany
  • Holger Sültmann, Deutsches Krebsforschungszentrum Heidelberg - Germany
  • Ruggero De Maria, IRCCS Istituti Fisioterapici Ospitalieri - Italy
  • Claudio Luchinat, Università degli Studi di Firenze - Italy
  • Fabrizio DAdda Di Fagagna, IFOM Foundation - Italy
  • Atsumi Nitta, University of Toyama - Japan
  • Kaoru Goto, Yamagata University School of Medicine - Japan
  • Miranda Van Eck, Universiteit Leiden - Netherlands
  • Ulrich Schotten, Universiteit Maastricht - Netherlands
  • Albert K. Groen, University of Groningen - Netherlands
  • Albert J.R. Heck, Utrecht University - Netherlands
  • Montserrat Pinent Armengol, Universitat Rovira i Virgili - Spain
  • Jens Nielsen, Chalmers University of Technology - Sweden
  • Ingemar Björkhem, Karolinska University Hospital - Sweden
  • Hanns-Ulrich Marschall, University of Gothenburg - Sweden
  • Birthe Fahrenkrog, Universität Basel - Switzerland
  • Bruno Stieger, University of Zurich - Switzerland
  • Johan Auwerx, École polytechnique fédérale de Lausanne - Switzerland
  • Maud Frieden, University of Geneva - Switzerland
  • Martin Kussmann, Nestlé Research Center - Switzerland
  • Nicolas Demaurex, University of Geneva Medical Center - Switzerland
  • E. E. Kershaw, University of Pittsburgh Medical Center - USA
  • Hartmut W. Jaeschke, University of Kansas - USA
  • Donald M. Bers, University of California at Davis - USA
  • David D. Moore, University of California Berkeley - USA
  • Gyorgy Hajnoczky, Thomas Jefferson University - USA
  • Michael Xi Zhu, The University of Texas Health Science Center - USA
  • Vittorio Sebastiano, Stanford University School of Medicine - USA
  • Dawn L. Brasaemle, RUTGERS - The State University of New Jersey - USA
  • Robert J. Schneider, New York University Medical Center - USA
  • Jesse C. Hay, The University of Montana - USA
  • Indu S. Ambudkar, National Institutes of Health - USA
  • Snorri S. Thorgeirsson, National Cancer Institute / NIH - USA
  • Robert A. Roth, Michigan State University - USA
  • Robert V. Farese, Memorial Sloan Kettering Cancer Center - USA
  • Matthew G. Vander Heiden, MIT - Massachusetts Institute of Technology - USA
  • John Quackenbush, Dana-Farber Cancer Institute - USA
  • Ira Jay Goldberg, Columbia University Medical Center - USA
  • Jeffery D. Molkentin, Cincinnati Children´s Medical Center - USA
  • Lutz Birnbaumer, National Institutes of Health - USA
  • Peter J. Voshol, University of Cambridge
  • Michael R. Duchen, University College London
  • György Szabadkai, University College London
  • Ian P. M. Tomlinson, The University of Oxford
  • Francis Antony Lai, Cardiff University
  • David A. Eisner, University of Manchester
  • Nigel Carter, Sanger Centre
  • Barbara Casadei, University of Oxford

Research Output

  • 29401 Citations
  • 604 Publications

Discovering
what
matters.

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