IBDome

IBDome

Zlatko Trajanoski (ORCID: 0000-0002-0636-7351)

DACH: Österreich - Deutschland - Schweiz

Disciplines

Biology (100%)

Keywords

    Inflammatory Bowel Deseases, Database, Bioinformatics

Abstract Final report

The IBDome project will develop a web-accessible database that integrates large scale omic-datasets from IBD patients with corresponding clinical disease status. The database will include two types of data: 1) data from deep profiling using cutting-edge technologies on a specified exemplary patient cohort including controls provided by four preselected projects of the consortium, and 2) data from broad profiling of a large number of samples from the existing tissue banks in Erlangen and Berlin.

The IBDome project developed a web-accessible database that integrates large scale omic-datasets from IBD patients with corresponding clinical disease status. The database includes two types of data: 1) data from deep profiling using cutting-edge technologies on a specified exemplary patient cohort including controls provided by four preselected projects of the consortium, and 2) data from broad profiling of a large number of samples from the existing tissue banks in Erlangen and Berlin.
Research institution(s)
International project participants

Research Output

  • 1971 Citations
  • 16 Publications
Publications
  • 2021
    Title Dynamic, Transient, and Robust Increase in the Innervation of the Inflamed Mucosa in Inflammatory Bowel Diseases
    DOI 10.3390/cells10092253
    Type Journal Article
    Author Acera M
    Journal Cells
    Pages 2253
    Link Publication
  • 2019
    Title Advancing cancer immunotherapy: a vision for the field
    DOI 10.1186/s13073-019-0662-6
    Type Journal Article
    Author De Miranda N
    Journal Genome Medicine
    Pages 51
    Link Publication
  • 2020
    Title Scirpy: a Scanpy extension for analyzing single-cell T-cell receptor-sequencing data
    DOI 10.1093/bioinformatics/btaa611
    Type Journal Article
    Author Sturm G
    Journal Bioinformatics
    Pages 4817-4818
    Link Publication
  • 2020
    Title CD39 Identifies the CD4+ Tumor-Specific T-cell Population in Human Cancer
    DOI 10.1158/2326-6066.cir-20-0270
    Type Journal Article
    Author Kortekaas K
    Journal Cancer Immunology Research
    Pages 1311-1321
    Link Publication
  • 2020
    Title Scirpy: A Scanpy extension for analyzing single-cell T-cell receptor sequencing data
    DOI 10.1101/2020.04.10.035865
    Type Preprint
    Author Sturm G
    Pages 2020.04.10.035865
    Link Publication
  • 2019
    Title Guadecitabine Plus Ipilimumab in Unresectable Melanoma: The NIBIT-M4 Clinical Trial
    DOI 10.1158/1078-0432.ccr-19-1335
    Type Journal Article
    Author Di Giacomo A
    Journal Clinical Cancer Research
    Pages 7351-7362
  • 2019
    Title Additional file 2: of Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data
    DOI 10.6084/m9.figshare.8186231.v1
    Type Other
    Author Finotello F
    Link Publication
  • 2019
    Title Additional file 2: of Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data
    DOI 10.6084/m9.figshare.8186231
    Type Other
    Author Finotello F
    Link Publication
  • 2022
    Title High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer
    DOI 10.1101/2022.05.09.491204
    Type Preprint
    Author Salcher S
    Pages 2022.05.09.491204
    Link Publication
  • 2022
    Title Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer
    DOI 10.1101/2022.09.16.508204
    Type Preprint
    Author Plattner C
    Pages 2022.09.16.508204
    Link Publication
  • 2021
    Title NKG2A is a late immune checkpoint on CD8 T cells and marks repeated stimulation and cell division
    DOI 10.1002/ijc.33859
    Type Journal Article
    Author Borst L
    Journal International Journal of Cancer
    Pages 688-704
    Link Publication
  • 2022
    Title High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer
    DOI 10.1016/j.ccell.2022.10.008
    Type Journal Article
    Author Salcher S
    Journal Cancer Cell
    Link Publication
  • 2019
    Title Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data
    DOI 10.1186/s13073-019-0638-6
    Type Journal Article
    Author Finotello F
    Journal Genome Medicine
    Pages 34
    Link Publication
  • 2019
    Title Next-generation computational tools for interrogating cancer immunity
    DOI 10.1038/s41576-019-0166-7
    Type Journal Article
    Author Finotello F
    Journal Nature Reviews Genetics
    Pages 724-746
  • 2022
    Title Tumor-specific T cells support chemokine-driven spatial organization of intratumoral immune microaggregates needed for long survival
    DOI 10.1136/jitc-2021-004346
    Type Journal Article
    Author Abdulrahman Z
    Journal Journal for ImmunoTherapy of Cancer
    Link Publication
  • 2022
    Title CD161 expression and regulation defines rapidly responding effector CD4+ T cells associated with improved survival in HPV16-associated tumors
    DOI 10.1136/jitc-2021-003995
    Type Journal Article
    Author Duurland C
    Journal Journal for ImmunoTherapy of Cancer
    Link Publication