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ArtiPro

ArtiPro

Roberto Francesco Giovanni Viviani (ORCID: 0000-0002-7517-6006)
  • Grant DOI 10.55776/I5903
  • Funding program International - Multilateral Initiatives
  • Status ongoing
  • Start May 1, 2022
  • End April 30, 2026
  • Funding amount € 287,060
  • E-mail

ERA-NET: Permed

Disciplines

Clinical Medicine (40%); Medical-Theoretical Sciences, Pharmacy (60%)

Keywords

    Personalized Medicine, Depression, Biomarkers, Functional Imaging, Machine Learning

Abstract

Personalised medicine aims to predict therapeutic response according to a personal profile that includes clinical, biological, and genetic data. This project focuses on depression. It aims to establish an artificial intelligence platform that brings together data from clinical research on the components of these profiles with the purpose of identifying predictors for response to depression treatment. The results will be combined into a single data platform that enables the use of large multimodal datasets to develop predictive models of symptoms and outcome data, thus enhancing the impact of these data. Artificial intelligence approaches will be investigated to identify novel biomarkers that can predict response to treatment. This will help to develop of a decision support system for personalised therapy while identifying the specific ethical and legal requirements that need to be fulfilled.

Research institution(s)
  • Universität Innsbruck - 100%
International project participants
  • Nada Bozina, Universität Zagreb - Croatia
  • Catharina Scholl, Sonstige Forschungs- oder Entwicklungseinrichtungen - Germany
  • Noam Shomron, Tel-Aviv University - Israel
  • Maria Giulia Bacalini, University of Bologna - Italy
  • Espen Molden, University of Oslo - Norway

Research Output

  • 16 Citations
  • 8 Publications
Publications
  • 2024
    Title The fMRI global signal and its association with the signal from cranial bone
    DOI 10.1101/2024.03.27.587003
    Type Preprint
    Author Huber D
    Pages 2024.03.27.587003
    Link Publication
  • 2024
    Title The dark side of personality functioning: associations between antisocial cognitions, personality functioning (AMPD), empathy and mentalisation
    DOI 10.3389/fpsyt.2024.1377177
    Type Journal Article
    Author Rabl L
    Journal Frontiers in Psychiatry
    Pages 1377177
    Link Publication
  • 2024
    Title Phenotypic Models of Drug–Drug-Gene Interactions Mediated by Cytochrome Drug-Metabolizing Enzymes
    DOI 10.1002/cpt.3188
    Type Journal Article
    Author Viviani R
    Journal Clinical Pharmacology & Therapeutics
    Pages 592-601
    Link Publication
  • 2025
    Title Pharmacogenetic guided drug therapy – how to deal with phenoconversion in polypharmacy
    DOI 10.1080/17425255.2025.2451440
    Type Journal Article
    Author Stingl J
    Journal Expert Opinion on Drug Metabolism & Toxicology
    Pages 399-407
    Link Publication
  • 2024
    Title The fMRI global signal and its association with the signal from cranial bone
    DOI 10.1016/j.neuroimage.2024.120754
    Type Journal Article
    Author Huber D
    Journal NeuroImage
    Pages 120754
    Link Publication
  • 2024
    Title Cognitive effort and reward. Functional imaging of time on task and the involvement of dopaminergic and cholinergic substrates
    DOI 10.1101/2024.12.12.628171
    Type Preprint
    Author Orsini C
    Pages 2024.12.12.628171
    Link Publication
  • 2023
    Title Phenotypic models of drug-drug-gene interactions mediated by cytochrome drug-metabolizing enzymes
    DOI 10.1101/2023.11.02.23297749
    Type Preprint
    Author Viviani R
    Pages 2023.11.02.23297749
    Link Publication
  • 2022
    Title Pharmacogenetic Dose Modeling Based on CYP2C19 Allelic Phenotypes
    DOI 10.3390/pharmaceutics14122833
    Type Journal Article
    Author Stingl J
    Journal Pharmaceutics
    Pages 2833
    Link Publication

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