Designer Receptor Gene Therapy constructed for Parkinson’s

Disciplines

Computer Sciences (10%); Medical-Theoretical Sciences, Pharmacy (30%); Medical Biotechnology (60%)

Keywords

Neuroscience, Gene Therapy, Designer Receptor, Parkinson's Disease

Abstract

Within this FWF Stand-Alone Project we will use state of the art computational methods to design custom-made proteins. Following intensive in vitro characterisation of these designer receptors with different cell based assays and electrophysiology, we will evaluate their efficacy in multiple animal models. The overall aim of this project is the development of novel gene therapies targeting Parkinsons disease.