Disciplines
Biology (60%); Geosciences (25%); Clinical Medicine (15%)
Keywords
Arginine Kinase,
Crustaceans,
Insects,
Allergenicity,
Immunological Targeting,
Cross-reactivity
Abstract
Arginine kinase is a widespread enzyme in invertebrates and a major trigger of food allergies,
particularly found in crustaceans and insects. This FWF-funded project aims to structurally
and immunologically characterize arginine kinases from seafood and insect-based food
sources. The goal is to determine novel protein structures, map IgE-binding epitopes, and
develop hypoallergenic peptides for future therapy. The findings will support improved
allergy diagnostics and treatment, laying the groundwork for epitope-based immunotherapy.