Fine-tuning 8H-quinolines to target resistance in cancer

Fine-tuning 8H-quinolines to target resistance in cancer

Gergely Szakacs (ORCID: 0000-0002-9311-7827)

Disciplines

Chemistry (50%); Medical-Theoretical Sciences, Pharmacy (50%)

Keywords

    Multidrug Resistance, P-glycoprotein, Cancer, Collateral Sensitivity, Anticancer Chelators, Solution Speciation

Research institution(s)
International project participants

Research Output

  • 2 Publications
Publications
  • 2025
    Title Organometallic Half-Sandwich Complexes of 1,10-Phenanthroline Derivatives with Improved Solubility, Albumin-Binding, and Nanoformulation Potential Targeting Drug Resistance in Cancer
    DOI 10.1021/acs.inorgchem.5c01556
    Type Journal Article
    Author Va´Rkonyi E
    Journal Inorganic Chemistry
    Pages 14914-14932
    Link Publication
  • 2025
    Title Comparative study of multidrug resistance-targeting 8-hydroxyquinoline-amino acid conjugates: anticancer effect, interaction with human serum albumin and organic anion transporting polypeptides
    DOI 10.1016/j.ejps.2025.107187
    Type Journal Article
    Author Dömötör O
    Journal European Journal of Pharmaceutical Sciences
    Pages 107187
    Link Publication