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Cell Communication in Health and Disease

Cell Communication in Health and Disease

Stefan Böhm (ORCID: 0000-0002-0205-2459)
  • Grant DOI 10.55776/W1205
  • Funding program Doctoral Programs
  • Status ended
  • Start September 1, 2006
  • End September 30, 2020
  • Funding amount € 9,587,217
  • Project website
  • E-mail

Disciplines

Medical-Theoretical Sciences, Pharmacy (100%)

Abstract

The coordinated communication between cells is the basis for the regular function of an entire organism. If this cell communication is disturbed, affected tissues and organs fail to fulfil their functions and diseases develop. This applies not only to rare diseases with monogenetic causes, but also to more widespread pathologic conditions, such as neurodegenerative diseases, atherosclerosis, or chronic inflammatory diseases. Hence, the understanding of cellular communication is an essential prerequisite for the perception of pathological alterations associated with certain malfunctions and thus the basis for therapeutic intervention and for the development new therapeutic agents. The doctoral training course Cell Communication in Health and Disease` - CCHD - will provide highly talented and well educated students with challenging interrelated research topics derived from one of the following four themes of biomedical sciences: Neurobiology, Vascular Biology, Immunology, and Inflammation Research. Although these topics appear heterogeneous, they all focus on the communication between cells in either health or various disease states. Numerous analogous mechanisms have been described within these research themes, and the CCHD students will learn in interdisciplinary courses how to abstract from their own thesis projects into the other research themes. Moreover, CCHD integrates basic, applied, and clinical sciences to provide comprehensive and thorough up-to-date research training in these important fields of biomedical research. CCHD students will be exposed to the entire spectrum of experimental techniques used in the participating laboratories and will obtain hands-on experience. Due to foreign members in theses committees, international speakers in CCHD workshops and theses symposia, and because of participation at international courses and scientific meetings and spending one semester abroad, CCHD students will become familiar with international research collaborations. Because of additional training by representatives of the pharmaceutical industry, CCHD students will also gain insight into non-academic research. The strong cluster of scientists working in the research fields of CCHD at the Medical University of Vienna provides the critical mass, the infrastructure, and the stimulating research and training environment to ensure success of this doctoral study program. Thus, the graduates of CCHD will be able to acquire all qualifications that prepare them for international careers in biomedical and other life sciences.

Consortium
  • Christoph J. Binder, Medizinische Universität Wien
    consortium member (01.09.2006 - 30.09.2020)
  • Daniela D. Pollak-Monje Quiroga, Medizinische Universität Wien
    consortium member (01.09.2006 - 30.09.2020)
  • Hannes Stockinger, Medizinische Universität Wien
    consortium member (01.09.2006 - 30.09.2020)
  • Irene M. Lang, Medizinische Universität Wien
    consortium member (01.09.2006 - 30.09.2020)
  • Johannes B. Huppa, Charité - Universitätsmedizin Berlin
    consortium member (01.09.2006 - 30.09.2020)
  • Johannes Berger, Medizinische Universität Wien
    consortium member (01.09.2006 - 30.09.2020)
  • Jürgen Sandkühler, Medizinische Universität Wien
    consortium member (01.09.2006 - 30.09.2020)
  • Kaan Boztug, CeMM – Forschungszentrum für Molekulare Medizin GmbH
    consortium member (01.09.2006 - 30.09.2020)
  • Michael Freissmuth, Medizinische Universität Wien
    consortium member (01.09.2006 - 30.09.2020)
  • Stefan Böhm, Medizinische Universität Wien
    consortium member (01.09.2006 - 30.09.2020)
  • Sylvia Knapp, Medizinische Universität Wien
    consortium member (01.09.2006 - 30.09.2020)
  • Thomas Klausberger, Medizinische Universität Wien
    consortium member (01.09.2006 - 30.09.2020)
  • Thomas M. Stulnig, Medizinische Universität Wien
    consortium member (01.09.2006 - 30.09.2020)
Research institution(s)
  • CeMM – Forschungszentrum für Molekulare Medizin GmbH
  • Institute of Science and Technology Austria - ISTA
  • Medizinische Universität Wien
  • Medizinische Universität Wien
  • Medizinische Universität Wien
Project participants
  • Andrew Rees, Medizinische Universität Wien , national collaboration partner
  • Peter M. Jonas, Institute of Science and Technology Austria - ISTA , associated research partner
  • Jozsef Csicsvari, Institute of Science and Technology Austria - ISTA , national collaboration partner
International project participants
  • Chi Chung Hui, University of Toronto - Canada
  • Vaclav Horejsi, Academy of Sciences of the Czech Republic - Czechia
  • Edzard Spillner, Aarhus University - Denmark
  • Kari Alitalo, Helsinki University - Finland
  • Joel Bockaert, Centre CNRS-UPR34094 - France
  • Antoine Triller, Ecole Normale Supérieure de Paris - France
  • Alain Tedgui, INSERM - France
  • Giuseppina Caligiuri, INSERM - France
  • Daniel Choquet, University of Bordeaux 2 - France
  • Roland S. Liblau, University of Toulouse - France
  • Bodo Grimbacher, Universitätsklinikum Freiburg - Germany
  • Bernhard Nieswandt, Universitätsklinik Würzburg - Germany
  • Andreas Pichlmair, Technische Universität München - Germany
  • Kai Simons, Max-Planck-Institut für - Germany
  • Hartmut Wekerle, Max-Planck-Gesellschaft - Germany
  • Armin Reininger, Ludwig-Maximilians-Universität München - Germany
  • Edgar Meinl, Klinikum der Ludwig-Maximilians-Universität München - Germany
  • Heinrich Betz, Max-Planck-Institut für Hirnforschung - Germany
  • Klaus T. Preissner, Justus Liebig-Universität Giessen - Germany
  • Claudia Sommer, Julius-Maximilians-Universität Würzburg - Germany
  • Ulrich Walter, Johannes Gutenberg Universität Mainz - Germany
  • Susanne Neschen, Helmholtz Zentrum München - Germany
  • Michael Stürzl, Friedrich-Alexander-Universität Erlangen-Nürnberg - Germany
  • Paul Saftig, Christian Albrechts Universität Kiel - Germany
  • Christoph Klein, Klinikum der Ludwig-Maximilians-Universität München - Germany
  • Steven W. Kerrigan, Royal College of Surgeons in Ireland - Ireland
  • Saverio Cinti, Universita Politecnica delle Marche - Italy
  • Francesco Blasi, Vita Salute San Raffaele and DIBIT - Italy
  • Kazuo Fujihara, Fukushima Medical University - Japan
  • Hiroshi Matsuda, Tokyo University of Agriculture and Technology - Japan
  • Tom Van Der Poll, Universiteit van Amsterdam - Netherlands
  • Ronit Shiri-Sverdlov, Universiteit Maastricht - Netherlands
  • Thijn R. Brummelkamp, The Netherlands Cancer Institute - Netherlands
  • Joost C. M. Meijers, Amsterdam University Medical Centers - Netherlands
  • Miguel Soares, Instituto Gulbenkian de Ciencia - Portugal
  • Hanns Ulrich Zeilhofer, Eidgenössische Technische Hochschule Zürich - Switzerland
  • Andreas Lüthi, Friedrich Miescher Institute for Biomedical Research - Switzerland
  • Marco Colonna, Washington University School of Medicine - USA
  • Andrew Weyrich, University of Utah - USA
  • Rebecca P. Seal, University of Pittsburgh - USA
  • Frank C. Church, University of North Carolina at Chapel Hill - USA
  • Joseph L. Witztum, University of California, San Diego - USA
  • Christopher K. Glass, University of California, San Diego - USA
  • Jennifer L Whistler, University of California at Davis - USA
  • James J. Marsh, University of California San Diego - USA
  • Randy Schekman, University of California Berkeley - USA
  • Minoru Fukuda, Sanford-Burnham Medical Research Institute - USA
  • Jean-Laurent Casanova, The Rockefeller University - USA
  • Alejandro Schäffer, National Institutes of Health - USA
  • Claudia Lucchinetti, Mayo Clinic College of Medicine - USA
  • Nancy R. Cook, Harvard Medical School - USA
  • Leo E. Otterbein, Harvard Medical School - USA
  • F. H. Bach, Harvard Medical School - USA
  • Edda Fiebiger, Harvard Medical School - USA
  • Charles N. Serhan, Harvard Medical School - USA
  • Mark S. Shapiro, The University of Texas Health Science Center at San Antonio - USA
  • Vincent OConnor, University of Southampton - United Kingdom
  • David Dupret, University of Oxford - United Kingdom
  • Christopher Linington, University of Glasgow - United Kingdom
  • Ziad Mallat, University of Cambridge - United Kingdom
  • James A. Huntington, University of Cambridge - United Kingdom
  • William Wisden, University of Aberdeen - King´s College - United Kingdom
  • Sophia Karagiannis, King´s College London - United Kingdom
  • Peter Somogyi, The University of Oxford - United Kingdom
  • Marzia Malcangio, King´s College London - United Kingdom
  • Hannah J. Gould, King´s College London - United Kingdom
  • Anne Dell, Imperial College London - United Kingdom
  • Kenneth G. C. Smith, Universal College London - United Kingdom

Research Output

  • 17188 Citations
  • 241 Publications
Publications
  • 2024
    Title A triple cysteine motif as major determinant of the modulation of neuronal KV7 channels by the paracetamol metabolite N-acetyl-p-benzo quinone imine
    DOI 10.1111/bph.16380
    Type Journal Article
    Author Ray S
    Journal British Journal of Pharmacology
    Pages 2851-2868
    Link Publication
  • 2025
    Title Linking Transcriptional and Cellular Responses of Human and Murine Pneumococcal Pneumonia
    DOI 10.1101/2025.02.13.638069
    Type Preprint
    Author Gorki A
    Pages 2025.02.13.638069
  • 2012
    Title Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue
    DOI 10.1038/nm.2757
    Type Journal Article
    Author Kiefer F
    Journal Nature Medicine
    Pages 918-925
    Link Publication
  • 2012
    Title The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism
    DOI 10.1016/j.cmet.2012.04.023
    Type Journal Article
    Author Haschemi A
    Journal Cell Metabolism
    Pages 813-826
    Link Publication
  • 2012
    Title Long-chain n-3 PUFAs reduce adipose tissue and systemic inflammation in severely obese nondiabetic patients: a randomized controlled trial
    DOI 10.3945/ajcn.112.037432
    Type Journal Article
    Author Itariu B
    Journal The American Journal of Clinical Nutrition
    Pages 1137-1149
    Link Publication
  • 2012
    Title NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury
    DOI 10.1093/brain/aws012
    Type Journal Article
    Author Fischer M
    Journal Brain
    Pages 886-899
    Link Publication
  • 2012
    Title Concomitant facilitation of GABAA receptors and KV7 channels by the non-opioid analgesic flupirtine
    DOI 10.1111/j.1476-5381.2011.01821.x
    Type Journal Article
    Author Klinger F
    Journal British Journal of Pharmacology
    Pages 1631-1642
    Link Publication
  • 2012
    Title Temporal Dynamics of Parvalbumin-Expressing Axo-axonic and Basket Cells in the Rat Medial Prefrontal Cortex In Vivo
    DOI 10.1523/jneurosci.3475-12.2012
    Type Journal Article
    Author Massi L
    Journal The Journal of Neuroscience
    Pages 16496-16502
    Link Publication
  • 2012
    Title Reengineering the Collision Coupling and Diffusion Mode of the A2A-adenosine Receptor PALMITOYLATION IN HELIX 8 RELIEVES CONFINEMENT*
    DOI 10.1074/jbc.m112.393579
    Type Journal Article
    Author Keuerleber S
    Journal Journal of Biological Chemistry
    Pages 42104-42118
    Link Publication
  • 2012
    Title Monitoring neutrophils and platelets during casein-induced anaphylaxis in an experimental BALB/c mouse model
    DOI 10.1111/j.1365-2222.2012.04012.x
    Type Journal Article
    Author Krishnamurthy D
    Journal Clinical & Experimental Allergy
    Pages 1119-1128
  • 2012
    Title Interleukin-10: An Anti-Inflammatory Marker To Target Atherosclerotic Lesions via PEGylated Liposomes
    DOI 10.1021/mp300316n
    Type Journal Article
    Author Almer G
    Journal Molecular Pharmaceutics
    Pages 175-186
    Link Publication
  • 2012
    Title Prospects of Transcript Profiling for mRNAs and MicroRNAs Using Formalin-Fixed and Paraffin-Embedded Dissected Autoptic Multiple Sclerosis Lesions
    DOI 10.1111/j.1750-3639.2012.00564.x
    Type Journal Article
    Author Eisele S
    Journal Brain Pathology
    Pages 607-618
    Link Publication
  • 2012
    Title An unfolded variant of the major peanut allergen Ara h 2 with decreased anaphylactic potential
    DOI 10.1111/cea.12031
    Type Journal Article
    Author Starkl P
    Journal Clinical & Experimental Allergy
    Pages 1801-1812
    Link Publication
  • 2012
    Title Expression of G Protein-Coupled Receptor 19 in Human Lung Cancer Cells Is Triggered by Entry into S-Phase and Supports G2–M Cell-Cycle Progression
    DOI 10.1158/1541-7786.mcr-12-0139
    Type Journal Article
    Author Kastner S
    Journal Molecular Cancer Research
    Pages 1343-1358
    Link Publication
  • 2012
    Title Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease
    DOI 10.1194/jlr.m025445
    Type Journal Article
    Author Amir S
    Journal Journal of Lipid Research
    Pages 1316-1326
    Link Publication
  • 2012
    Title Functional and physical interactions between P2Y receptors and ion channels
    DOI 10.1186/2050-6511-13-s1-a61
    Type Journal Article
    Author Gafar H
    Journal BMC Pharmacology and Toxicology
    Link Publication
  • 2012
    Title The Thr715Pro variant impairs terminal glycosylation of P-selectin
    DOI 10.1160/th12-01-0047
    Type Journal Article
    Author Subramanian H
    Journal Thrombosis and Haemostasis
    Pages 963-972
    Link Publication
  • 2012
    Title VEGF-induced endothelial cell migration requires urokinase receptor (uPAR)-dependent integrin redistribution
    DOI 10.1093/cvr/cvs017
    Type Journal Article
    Author Alexander R
    Journal Cardiovascular Research
    Pages 125-135
    Link Publication
  • 2012
    Title Establishing an allergic eczema model employing recombinant house dust mite allergens Der p 1 and Der p 2 in BALB/c mice
    DOI 10.1111/exd.12015
    Type Journal Article
    Author Szalai K
    Journal Experimental Dermatology
    Pages 842-846
    Link Publication
  • 2012
    Title The Interferon Stimulated Gene 12 Inactivates Vasculoprotective Functions of NR4A Nuclear Receptors
    DOI 10.1161/circresaha.111.258814
    Type Journal Article
    Author Papac-Milicevic N
    Journal Circulation Research
    Link Publication
  • 2011
    Title Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice
    DOI 10.1007/s00125-011-2170-0
    Type Journal Article
    Author Kiefer F
    Journal Diabetologia
    Pages 2132-2142
    Link Publication
  • 2011
    Title Soluble M6P/IGF2R Released by TACE Controls Angiogenesis via Blocking Plasminogen Activation
    DOI 10.1161/circresaha.110.234732
    Type Journal Article
    Author Leksa V
    Journal Circulation Research
    Pages 676-685
    Link Publication
  • 2011
    Title Why could passive Immunoglobulin E antibody therapy be safe in clinical oncology?
    DOI 10.1111/j.1365-2222.2011.03764.x
    Type Journal Article
    Author Jensen-Jarolim E
    Journal Clinical & Experimental Allergy
    Pages 1337-1340
    Link Publication
  • 2011
    Title Signal Integration and Coincidence Detection in the Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) Cascade CONCOMITANT ACTIVATION OF RECEPTOR TYROSINE KINASES AND OF LRP-1 LEADS TO SUSTAINED ERK PHOSPHORYLATION VIA DOWN-
    DOI 10.1074/jbc.m111.221903
    Type Journal Article
    Author Geetha N
    Journal Journal of Biological Chemistry
    Pages 25663-25674
    Link Publication
  • 2011
    Title IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA
    DOI 10.1038/ni.2048
    Type Journal Article
    Author Pichlmair A
    Journal Nature Immunology
    Pages 624-630
  • 2011
    Title Spatio-temporal expression analysis of the calcium-binding protein calumenin in the rodent brain
    DOI 10.1016/j.neuroscience.2011.11.069
    Type Journal Article
    Author Vasiljevic M
    Journal Neuroscience
    Pages 29-41
    Link Publication
  • 2011
    Title Pathogenic T cell responses against aquaporin 4
    DOI 10.1007/s00401-011-0824-0
    Type Journal Article
    Author Pohl M
    Journal Acta Neuropathologica
    Pages 21
    Link Publication
  • 2011
    Title Cancer vaccines inducing antibody production: more pros than cons
    DOI 10.1586/erv.11.105
    Type Journal Article
    Author Jensen-Jarolim E
    Journal Expert Review of Vaccines
    Pages 1281-1289
  • 2011
    Title Osteopontin Is an Activator of Human Adipose Tissue Macrophages and Directly Affects Adipocyte Function
    DOI 10.1210/en.2010-1328
    Type Journal Article
    Author Zeyda M
    Journal Endocrinology
    Pages 2219-2227
    Link Publication
  • 2011
    Title The Serotonin Transporter Is an Exclusive Client of the Coat Protein Complex II (COPII) Component SEC24C*
    DOI 10.1074/jbc.m111.230037
    Type Journal Article
    Author Sucic S
    Journal Journal of Biological Chemistry
    Pages 16482-16490
    Link Publication
  • 2011
    Title Distribution of M-channel subunits KCNQ2 and KCNQ3 in rat hippocampus
    DOI 10.1016/j.neuroimage.2011.07.003
    Type Journal Article
    Author Klinger F
    Journal NeuroImage
    Pages 761-769
    Link Publication
  • 2011
    Title Nucleotides control the excitability of sensory neurons via two P2Y receptors and a bifurcated signaling cascade
    DOI 10.1016/j.pain.2011.04.016
    Type Journal Article
    Author Yousuf A
    Journal Pain
    Pages 1899-1908
    Link Publication
  • 2015
    Title The anticonvulsant retigabine is a subtype selective modulator of GABAA receptors
    DOI 10.1111/epi.12950
    Type Journal Article
    Author Treven M
    Journal Epilepsia
    Pages 647-657
    Link Publication
  • 2015
    Title Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display
    DOI 10.1371/journal.pone.0127169
    Type Journal Article
    Author Keller T
    Journal PLOS ONE
    Link Publication
  • 2015
    Title Nitration of ß-Lactoglobulin but Not of Ovomucoid Enhances Anaphylactic Responses in Food Allergic Mice
    DOI 10.1371/journal.pone.0126279
    Type Journal Article
    Author Diesner S
    Journal PLOS ONE
    Link Publication
  • 2015
    Title Derivation of a new parametric impulse response matrix utilized for nodal wind load identification by response measurement
    DOI 10.1016/j.jsv.2014.12.027
    Type Journal Article
    Author Amiri A
    Journal Journal of Sound and Vibration
    Pages 101-113
    Link Publication
  • 2014
    Title Impact of Age and Metabolic Syndrome on the Adipokine Profile in Childhood and Adult Obesity
    DOI 10.1055/s-0034-1375647
    Type Journal Article
    Author Weghuber D
    Journal Experimental and Clinical Endocrinology & Diabetes (Barth)
    Pages 363-367
  • 2014
    Title Axonal Targeting of the Serotonin Transporter in Cultured Rat Dorsal Raphe Neurons Is Specified by SEC24C-Dependent Export from the Endoplasmic Reticulum
    DOI 10.1523/jneurosci.2991-13.2014
    Type Journal Article
    Author Montgomery T
    Journal The Journal of Neuroscience
    Pages 6344-6351
    Link Publication
  • 2014
    Title The Triggering Receptor Expressed on Myeloid Cells 2 Inhibits Complement Component 1q Effector Mechanisms and Exerts Detrimental Effects during Pneumococcal Pneumonia
    DOI 10.1371/journal.ppat.1004167
    Type Journal Article
    Author Sharif O
    Journal PLoS Pathogens
    Link Publication
  • 2014
    Title Association between the rs342293 polymorphism and adverse cardiac events in patients undergoing percutaneous coronary intervention
    DOI 10.1160/th13-09-0757
    Type Journal Article
    Author Siller-Matula J
    Journal Thrombosis and Haemostasis
    Pages 1060-1066
  • 2014
    Title Excitation of rat sympathetic neurons via M1 muscarinic receptors independently of Kv7 channels
    DOI 10.1007/s00424-014-1487-1
    Type Journal Article
    Author Salzer I
    Journal Pflügers Archiv - European Journal of Physiology
    Pages 2289-2303
    Link Publication
  • 2014
    Title Thymic stromal lymphopoietin is expressed in the intact central nervous system and upregulated in the myelin-degenerative central nervous system
    DOI 10.1002/glia.22662
    Type Journal Article
    Author Kitic M
    Journal Glia
    Pages 1066-1074
    Link Publication
  • 2014
    Title Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man
    DOI 10.1016/j.cell.2014.04.043
    Type Journal Article
    Author Jais A
    Journal Cell
    Pages 25-40
    Link Publication
  • 2008
    Title After Injection into the Striatum, in Vitro-Differentiated Microglia- and Bone Marrow-Derived Dendritic Cells Can Leave the Central Nervous System via the Blood Stream
    DOI 10.2353/ajpath.2008.080234
    Type Journal Article
    Author Hochmeister S
    Journal The American Journal of Pathology
    Pages 1669-1681
    Link Publication
  • 2008
    Title Restricted Collision Coupling of the A2A Receptor Revisited EVIDENCE FOR PHYSICAL SEPARATION OF TWO SIGNALING CASCADES*
    DOI 10.1074/jbc.m706275200
    Type Journal Article
    Author Charalambous C
    Journal Journal of Biological Chemistry
    Pages 9276-9288
    Link Publication
  • 2008
    Title Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells
    DOI 10.1007/s00262-008-0607-1
    Type Journal Article
    Author Karagiannis P
    Journal Cancer Immunology, Immunotherapy
    Pages 915-930
    Link Publication
  • 2008
    Title Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A–induced hepatitis
    DOI 10.1002/hep.22401
    Type Journal Article
    Author Beldi G
    Journal Hepatology
    Pages 841-852
    Link Publication
  • 2008
    Title A membrane network of receptors and enzymes for adenine nucleotides and nucleosides
    DOI 10.1186/1471-2210-8-s1-a40
    Type Journal Article
    Author Schicker K
    Journal BMC Pharmacology
    Link Publication
  • 2008
    Title The non-opioid analgesic flupirtine is a modulator of GABAA receptors involved in pain sensation
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    Title Elevated oxytocin and noradrenaline indicate higher stress levels in allergic rhinitis patients: Implications for the skin prick diagnosis in a pilot study
    DOI 10.1371/journal.pone.0196879
    Type Journal Article
    Author Gotovina J
    Journal PLOS ONE
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  • 2018
    Title Lymphatic exosomes promote dendritic cell migration along guidance cues
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    Journal Journal of Cell Biology
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  • 2018
    Title An unsuspected role for organic cation transporter 3 in the actions of amphetamine
    DOI 10.1038/s41386-018-0053-5
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    Author Mayer F
    Journal Neuropsychopharmacology
    Pages 2408-2417
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  • 2018
    Title Near infrared photoimmunotherapy targeting bladder cancer with a canine anti-epidermal growth factor receptor (EGFR) antibody
    DOI 10.18632/oncotarget.24876
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    Author Nagaya T
    Journal Oncotarget
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    Title Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency
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    Author Van Rijn J
    Journal Gastroenterology
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  • 2018
    Title Breast cancer metastasis through the lympho-vascular system
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    Author Nathanson S
    Journal Clinical & Experimental Metastasis
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  • 2018
    Title Bidirectional Regulation of COX-2 Expression Between Cancer Cells and Macrophages
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    Author Carvalho M
    Journal Anticancer Research
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  • 2018
    Title AllergoOncology: Generating a canine anticancer IgE against the epidermal growth factor receptor
    DOI 10.1016/j.jaci.2018.04.021
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    Author Fazekas-Singer J
    Journal Journal of Allergy and Clinical Immunology
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  • 2018
    Title Extracellular Purine Metabolism Is the Switchboard of Immunosuppressive Macrophages and a Novel Target to Treat Diseases With Macrophage Imbalances
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    Author Ohradanova-Repic A
    Journal Frontiers in Immunology
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  • 2018
    Title Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage
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    Journal Gut
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  • 2013
    Title IgE-based immunotherapy of cancer: challenges and chances
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    Journal Allergy
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    Title Iron and neurodegeneration in the multiple sclerosis brain
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    Journal Annals of Neurology
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  • 2013
    Title T cell-activation in neuromyelitis optica lesions plays a role in their formation
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    Author Pohl M
    Journal Acta Neuropathologica Communications
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  • 2013
    Title Mechanism of hERG Channel Block by the Psychoactive Indole Alkaloid Ibogaine
    DOI 10.1124/jpet.113.209643
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    Author Thurner P
    Journal The Journal of Pharmacology and Experimental Therapeutics
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  • 2013
    Title Glutathione exposes sequential IgE-epitopes in ovomucoid relevant in persistent egg allergy
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    Journal Molecular Nutrition & Food Research
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  • 2013
    Title Neurogenic neuroinflammation: inflammatory CNS reactions in response to neuronal activity
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    Author Xanthos D
    Journal Nature Reviews Neuroscience
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  • 2013
    Title Protamine nanoparticles with CpG-oligodeoxynucleotide prevent an allergen-induced Th2-response in BALB/c mice
    DOI 10.1016/j.ejpb.2013.03.003
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    Author Pali-Schöll I
    Journal European Journal of Pharmaceutics and Biopharmaceutics
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  • 2013
    Title Experimental characterization of the human non-sequence-specific nucleic acid interactome
    DOI 10.1186/gb-2013-14-7-r81
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    Journal Genome Biology
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    Title WAVE1 mediates suppression of phagocytosis by phospholipid-derived DAMPs
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    Journal Journal of Clinical Investigation
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    Title Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica
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    Author Misu T
    Journal Acta Neuropathologica
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  • 2013
    Title The parvalbumin-positive interneurons in the mouse dentate gyrus express GABAA receptor subunits alpha1, beta2, and delta along their extrasynaptic cell membrane
    DOI 10.1016/j.neuroscience.2013.09.019
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    Journal Neuroscience
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  • 2013
    Title Enhanced Lymph Vessel Density, Remodeling, and Inflammation Are Reflected by Gene Expression Signatures in Dermal Lymphatic Endothelial Cells in Type 2 Diabetes
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    Title Switching the Clientele
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  • 2013
    Title Recruitment of a Cytoplasmic Chaperone Relay by the A2A Adenosine Receptor*
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    Journal Journal of Biological Chemistry
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  • 2013
    Title Prognostic value of neutrophils in patients with asymptomatic carotid artery disease
    DOI 10.1016/j.atherosclerosis.2013.10.002
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    Author Mayer F
    Journal Atherosclerosis
    Pages 274-280
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    Title Impaired Local Production of Proresolving Lipid Mediators in Obesity and 17-HDHA as a Potential Treatment for Obesity-Associated Inflammation
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    Journal Diabetes
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  • 2014
    Title Epicutaneously applied Der p 2 induces a strong TH2-biased antibody response in C57BL/6 mice, independent of functional TLR4
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    Journal Allergy
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  • 2014
    Title The Late Endosomal Transporter CD222 Directs the Spatial Distribution and Activity of Lck
    DOI 10.4049/jimmunol.1303349
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    Journal The Journal of Immunology
    Pages 2718-2732
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    Title Chaperoning of the A1-Adenosine Receptor by Endogenous Adenosine—An Extension of the Retaliatory Metabolite Concept
    DOI 10.1124/mol.114.094045
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    Author Kusek J
    Journal Molecular Pharmacology
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  • 2014
    Title VGluT3+ Primary Afferents Play Distinct Roles in Mechanical and Cold Hypersensitivity Depending on Pain Etiology
    DOI 10.1523/jneurosci.2157-14.2014
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    Author Draxler P
    Journal The Journal of Neuroscience
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  • 2014
    Title Adeno-Associated Virus-Like Particles as New Carriers for B-Cell Vaccines: Testing Immunogenicity and Safety in BALB/c Mice
    DOI 10.1089/vim.2014.0059
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    Author Manzano-Szalai K
    Journal Viral Immunology
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  • 2014
    Title Guanylate Binding Protein 1–Mediated Interaction of T Cell Antigen Receptor Signaling with the Cytoskeleton
    DOI 10.4049/jimmunol.1300377
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    Author Forster F
    Journal The Journal of Immunology
    Pages 771-781
  • 2013
    Title The Scavenger Receptor CD36 Downmodulates the Early Inflammatory Response while Enhancing Bacterial Phagocytosis during Pneumococcal Pneumonia
    DOI 10.4049/jimmunol.1202270
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    Author Sharif O
    Journal The Journal of Immunology
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  • 2013
    Title Intrastriatal injection of interleukin-1 beta triggers the formation of neuromyelitis optica-like lesions in NMO-IgG seropositive rats
    DOI 10.1186/2051-5960-1-5
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    Author Kitic M
    Journal Acta Neuropathologica Communications
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  • 2013
    Title Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes
    DOI 10.1172/jci67911
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    Author Warszawska J
    Journal Journal of Clinical Investigation
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  • 2015
    Title STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behavior
    DOI 10.1038/srep09009
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    Author Kong E
    Journal Scientific Reports
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  • 2015
    Title A Salt Bridge Linking the First Intracellular Loop with the C Terminus Facilitates the Folding of the Serotonin Transporter*
    DOI 10.1074/jbc.m115.641357
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    Journal Journal of Biological Chemistry
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  • 2015
    Title Advances in our understanding of mechanisms of venous thrombus resolution
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    Author Altmann J
    Journal Expert Review of Hematology
    Pages 69-78
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    Title Rapid multiplex analysis of lipid raft components with single-cell resolution
    DOI 10.1126/scisignal.aac5584
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    Author Schatzlmaier P
    Journal Science Signaling
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    Title Ligand Selectivity among the Dopamine and Serotonin Transporters Specified by the Forward Binding Reaction
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    Journal Molecular Pharmacology
    Pages 12-18
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    Title The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity
    DOI 10.1016/j.celrep.2015.05.006
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    Author Heinz L
    Journal Cell Reports
    Pages 1919-1928
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  • 2017
    Title Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters
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    Journal International Journal of Molecular Sciences
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  • 2017
    Title Heme and hemolysis in innate immunity: adding insult to injury
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    Journal Current Opinion in Immunology
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    Title Platelet-borne complement proteins and their role in platelet–bacteria interactions
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    Author Arbesu I
    Journal Journal of Thrombosis and Haemostasis
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  • 2016
    Title Comparison of the ß-Adrenergic Receptor Antagonists Landiolol and Esmolol: Receptor Selectivity, Partial Agonism, and Pharmacochaperoning Actions
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    Author Nasrollahi-Shirazi S
    Journal The Journal of Pharmacology and Experimental Therapeutics
    Pages 73-81
  • 2016
    Title Functional Rescue of a Misfolded Drosophila melanogaster Dopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones* ?
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    Journal Journal of Biological Chemistry
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  • 2016
    Title Peptide-based vaccination against OPN integrin binding sites does not improve cardio-metabolic disease in mice
    DOI 10.1016/j.imlet.2016.09.006
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    Author Grün N
    Journal Immunology Letters
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  • 2016
    Title Type I interferon promotes alveolar epithelial type II cell survival during pulmonary Streptococcus pneumoniae infection and sterile lung injury in mice
    DOI 10.1002/eji.201546201
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    Author Maier B
    Journal European Journal of Immunology
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  • 2016
    Title Membrane coordination of receptors and channels mediating the inhibition of neuronal ion currents by ADP
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    Author Gafar H
    Journal Purinergic Signalling
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  • 2016
    Title Increased expression of transient receptor potential canonical 6 (TRPC6) in differentiating human megakaryocytes
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    Author Ramanathan G
    Journal Cell Biology International
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  • 2016
    Title Divisions of Identified Parvalbumin-Expressing Basket Cells during Working Memory-Guided Decision Making
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    Journal Neuron
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  • 2016
    Title The brain-tumor related protein podoplanin regulates synaptic plasticity and hippocampus-dependent learning and memory
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    Author Cicvaric A
    Journal Annals of Medicine
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  • 2016
    Title Osteopontin affects macrophage polarization promoting endocytic but not inflammatory properties
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    Journal Obesity
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  • 2016
    Title Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
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    Author Leithner A
    Journal Nature Cell Biology
    Pages 1253-1259
  • 2016
    Title A time-resolved molecular map of the macrophage response to VSV infection
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    Journal npj Systems Biology and Applications
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  • 2016
    Title Why man's best friend, the dog, could also benefit from an anti-HER-2 vaccine
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    Journal Oncology Letters
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  • 2016
    Title Association of CD147 and Calcium Exporter PMCA4 Uncouples IL-2 Expression from Early TCR Signaling
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    Author Supper V
    Journal The Journal of Immunology
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    Title Trastuzumab mediates antibody-dependent cell-mediated cytotoxicity and phagocytosis to the same extent in both adjuvant and metastatic HER2/neu breast cancer patients
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    Author Petricevic B
    Journal Journal of Translational Medicine
    Pages 307
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  • 2013
    Title Human but Not Mouse Adipogenesis Is Critically Dependent on LMO3
    DOI 10.1016/j.cmet.2013.05.020
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    Author Lindroos J
    Journal Cell Metabolism
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  • 2013
    Title Mean platelet volume predicts outcome in patients with asymptomatic carotid artery disease
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    Author Mayer F
    Journal European Journal of Clinical Investigation
    Pages 22-28
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  • 2013
    Title Evaluating the effect of temperature induced water viscosity and density fluctuations on virus and DOC removal during river bank filtration – a scenario analysis
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    Journal River Systems
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    Title A reversible gene trap collection empowers haploid genetics in human cells
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    Journal Nature Methods
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  • 2013
    Title IGHV1-69-Encoded Antibodies Expressed in Chronic Lymphocytic Leukemia React with Malondialdehyde–Acetaldehyde Adduct, an Immunodominant Oxidation-Specific Epitope
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    Author Que X
    Journal PLoS ONE
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  • 2013
    Title Disease-specific molecular events in cortical multiple sclerosis lesions
    DOI 10.1093/brain/awt110
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    Author Fischer M
    Journal Brain
    Pages 1799-1815
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  • 2012
    Title Comparative oncology: ErbB-1 and ErbB-2 homologues in canine cancer are susceptible to cetuximab and trastuzumab targeting
    DOI 10.1016/j.molimm.2012.01.002
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    Author Singer J
    Journal Molecular Immunology
    Pages 200-209
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  • 2012
    Title SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi–goutières syndrome-associated mutations
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    Author Goncalves A
    Journal Human Mutation
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  • 2012
    Title Behavior-dependent specialization of identified hippocampal interneurons
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    Journal Nature Neuroscience
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  • 2012
    Title Viral immune modulators perturb the human molecular network by common and unique strategies
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    Author Pichlmair A
    Journal Nature
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    Title Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models
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    Journal Acta Neuropathologica
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  • 2014
    Title IgE-based Immunotherapy of Cancer -A Comparative Oncology Approach
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    Journal Journal of Carcinogenesis & Mutagenesis
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    Title A Cytosolic Relay of Heat Shock Proteins HSP70-1A and HSP90ß Monitors the Folding Trajectory of the Serotonin Transporter*
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    Title Tracking Single Serotonin Transporter Molecules at the Endoplasmic Reticulum and Plasma Membrane
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    Journal Biophysical Journal
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  • 2014
    Title The Major Cow Milk Allergen Bos d 5 Manipulates T-Helper Cells Depending on Its Load with Siderophore-Bound Iron
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    Journal PLoS ONE
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  • 2014
    Title Generation of a Canine Anti-EGFR (ErbB-1) Antibody for Passive Immunotherapy in Dog Cancer Patients
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    Journal Molecular Cancer Therapeutics
    Pages 1777-1790
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  • 2014
    Title Lck Mediates Signal Transmission from CD59 to the TCR/CD3 Pathway in Jurkat T Cells
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    Journal PLoS ONE
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  • 2014
    Title Bet v 1 from Birch Pollen Is a Lipocalin-like Protein Acting as Allergen Only When Devoid of Iron by Promoting Th2 Lymphocytes*
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    Journal Journal of Biological Chemistry
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  • 2014
    Title The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production
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    Author Eberle C
    Journal Virology
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  • 2014
    Title Triggering receptor expressed on myeloid cells-2 fine-tunes inflammatory responses in murine Gram-negative sepsis
    DOI 10.1096/fj.14-260067
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    Author Gawish R
    Journal The FASEB Journal
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    Title Gliogenic LTP spreads widely in nociceptive pathways
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    Author Kronschläger M
    Journal Science
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  • 2016
    Title Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions
    DOI 10.1038/ni.3590
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    Author Martins R
    Journal Nature Immunology
    Pages 1361-1372
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  • 2015
    Title Papain Degrades Tight Junction Proteins of Human Keratinocytes In Vitro and Sensitizes C57BL/6 Mice via the Skin Independent of its Enzymatic Activity or TLR4 Activation
    DOI 10.1038/jid.2015.58
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    Author Stremnitzer C
    Journal Journal of Investigative Dermatology
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    Title Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9
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    Author Lindner M
    Journal Brain
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  • 2015
    Title Crosstalk of carcinoembryonic antigen and transforming growth factor-ß via their receptors: comparing human and canine cancer
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    Journal Cancer Immunology, Immunotherapy
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  • 2015
    Title Translating clinical trials from human to veterinary oncology and back
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    Journal Journal of Translational Medicine
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  • 2015
    Title d Subunit-containing GABAA receptors are preferred targets for the centrally acting analgesic flupirtine
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    Journal British Journal of Pharmacology
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  • 2020
    Title Targeting foam cell formation in inflammatory brain diseases by the histone modifier MS-275
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    Author Zierfuss B
    Journal Annals of Clinical and Translational Neurology
    Pages 2161-2177
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  • 2020
    Title Unscrambling fluorophore blinking for comprehensive cluster detection via photoactivated localization microscopy
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    Author Platzer R
    Journal Nature Communications
    Pages 4993
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  • 2020
    Title Functional Impact of the G279S Substitution in the Adenosine A1-Receptor (A1R-G279S7.44), a Mutation Associated with Parkinson’s Disease
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    Author Nasrollahi-Shirazi S
    Journal Molecular Pharmacology
    Pages 250-266
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  • 2020
    Title Neutrophil Extracellular Traps Induce MCP-1 at the Culprit Site in ST-Segment Elevation Myocardial Infarction
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    Author Hofbauer T
    Journal Frontiers in Cell and Developmental Biology
    Pages 564169
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  • 2019
    Title The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection
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    Author Moskovskich A
    Pages 573253
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  • 2019
    Title Deciphering the microbiome shift during fermentation of medicinal plants
    DOI 10.1038/s41598-019-49799-2
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    Author Köberl M
    Journal Scientific Reports
    Pages 13461
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