Cell Communication in Health and Disease
Cell Communication in Health and Disease
Disciplines
Medical-Theoretical Sciences, Pharmacy (100%)
The coordinated communication between cells is the basis for the regular function of an entire organism. If this cell communication is disturbed, affected tissues and organs fail to fulfil their functions and diseases develop. This applies not only to rare diseases with monogenetic causes, but also to more widespread pathologic conditions, such as neurodegenerative diseases, atherosclerosis, or chronic inflammatory diseases. Hence, the understanding of cellular communication is an essential prerequisite for the perception of pathological alterations associated with certain malfunctions and thus the basis for therapeutic intervention and for the development new therapeutic agents. The doctoral training course Cell Communication in Health and Disease` - CCHD - will provide highly talented and well educated students with challenging interrelated research topics derived from one of the following four themes of biomedical sciences: Neurobiology, Vascular Biology, Immunology, and Inflammation Research. Although these topics appear heterogeneous, they all focus on the communication between cells in either health or various disease states. Numerous analogous mechanisms have been described within these research themes, and the CCHD students will learn in interdisciplinary courses how to abstract from their own thesis projects into the other research themes. Moreover, CCHD integrates basic, applied, and clinical sciences to provide comprehensive and thorough up-to-date research training in these important fields of biomedical research. CCHD students will be exposed to the entire spectrum of experimental techniques used in the participating laboratories and will obtain hands-on experience. Due to foreign members in theses committees, international speakers in CCHD workshops and theses symposia, and because of participation at international courses and scientific meetings and spending one semester abroad, CCHD students will become familiar with international research collaborations. Because of additional training by representatives of the pharmaceutical industry, CCHD students will also gain insight into non-academic research. The strong cluster of scientists working in the research fields of CCHD at the Medical University of Vienna provides the critical mass, the infrastructure, and the stimulating research and training environment to ensure success of this doctoral study program. Thus, the graduates of CCHD will be able to acquire all qualifications that prepare them for international careers in biomedical and other life sciences.
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consortium member (01.09.2006 - 30.09.2020)
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consortium member (01.09.2006 - 30.09.2020)
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consortium member (01.09.2006 - 30.09.2020)
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consortium member (01.09.2006 - 30.09.2020)
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consortium member (01.09.2006 - 30.09.2020)
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consortium member (01.09.2006 - 30.09.2020)
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consortium member (01.09.2006 - 30.09.2020)
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consortium member (01.09.2006 - 30.09.2020)
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consortium member (01.09.2006 - 30.09.2020)
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consortium member (01.09.2006 - 30.09.2020)
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consortium member (01.09.2006 - 30.09.2020)
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consortium member (01.09.2006 - 30.09.2020)
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consortium member (01.09.2006 - 30.09.2020)
- CeMM – Forschungszentrum für Molekulare Medizin GmbH
- Institute of Science and Technology Austria - ISTA
- Medizinische Universität Wien
- Medizinische Universität Wien
- Medizinische Universität Wien
- Andrew Rees, Medizinische Universität Wien , national collaboration partner
- Peter M. Jonas, Institute of Science and Technology Austria - ISTA , associated research partner
- Jozsef Csicsvari, Institute of Science and Technology Austria - ISTA , national collaboration partner
- Chi Chung Hui, University of Toronto - Canada
- Vaclav Horejsi, Academy of Sciences of the Czech Republic - Czechia
- Edzard Spillner, Aarhus University - Denmark
- Kari Alitalo, Helsinki University - Finland
- Joel Bockaert, Centre CNRS-UPR34094 - France
- Antoine Triller, Ecole Normale Supérieure de Paris - France
- Alain Tedgui, INSERM - France
- Giuseppina Caligiuri, INSERM - France
- Daniel Choquet, University of Bordeaux 2 - France
- Roland S. Liblau, University of Toulouse - France
- Bodo Grimbacher, Universitätsklinikum Freiburg - Germany
- Bernhard Nieswandt, Universitätsklinik Würzburg - Germany
- Andreas Pichlmair, Technische Universität München - Germany
- Kai Simons, Max-Planck-Institut für - Germany
- Hartmut Wekerle, Max-Planck-Gesellschaft - Germany
- Armin Reininger, Ludwig-Maximilians-Universität München - Germany
- Edgar Meinl, Klinikum der Ludwig-Maximilians-Universität München - Germany
- Heinrich Betz, Max-Planck-Institut für Hirnforschung - Germany
- Klaus T. Preissner, Justus Liebig-Universität Giessen - Germany
- Claudia Sommer, Julius-Maximilians-Universität Würzburg - Germany
- Ulrich Walter, Johannes Gutenberg Universität Mainz - Germany
- Susanne Neschen, Helmholtz Zentrum München - Germany
- Michael Stürzl, Friedrich-Alexander-Universität Erlangen-Nürnberg - Germany
- Paul Saftig, Christian Albrechts Universität Kiel - Germany
- Christoph Klein, Klinikum der Ludwig-Maximilians-Universität München - Germany
- Steven W. Kerrigan, Royal College of Surgeons in Ireland - Ireland
- Saverio Cinti, Universita Politecnica delle Marche - Italy
- Francesco Blasi, Vita Salute San Raffaele and DIBIT - Italy
- Kazuo Fujihara, Fukushima Medical University - Japan
- Hiroshi Matsuda, Tokyo University of Agriculture and Technology - Japan
- Tom Van Der Poll, Universiteit van Amsterdam - Netherlands
- Ronit Shiri-Sverdlov, Universiteit Maastricht - Netherlands
- Thijn R. Brummelkamp, The Netherlands Cancer Institute - Netherlands
- Joost C. M. Meijers, Amsterdam University Medical Centers - Netherlands
- Miguel Soares, Instituto Gulbenkian de Ciencia - Portugal
- Hanns Ulrich Zeilhofer, Eidgenössische Technische Hochschule Zürich - Switzerland
- Andreas Lüthi, Friedrich Miescher Institute for Biomedical Research - Switzerland
- Marco Colonna, Washington University School of Medicine - USA
- Andrew Weyrich, University of Utah - USA
- Rebecca P. Seal, University of Pittsburgh - USA
- Frank C. Church, University of North Carolina at Chapel Hill - USA
- Joseph L. Witztum, University of California, San Diego - USA
- Christopher K. Glass, University of California, San Diego - USA
- Jennifer L Whistler, University of California at Davis - USA
- James J. Marsh, University of California San Diego - USA
- Randy Schekman, University of California Berkeley - USA
- Minoru Fukuda, Sanford-Burnham Medical Research Institute - USA
- Jean-Laurent Casanova, The Rockefeller University - USA
- Alejandro Schäffer, National Institutes of Health - USA
- Claudia Lucchinetti, Mayo Clinic College of Medicine - USA
- Nancy R. Cook, Harvard Medical School - USA
- Leo E. Otterbein, Harvard Medical School - USA
- F. H. Bach, Harvard Medical School - USA
- Edda Fiebiger, Harvard Medical School - USA
- Charles N. Serhan, Harvard Medical School - USA
- Mark S. Shapiro, The University of Texas Health Science Center at San Antonio - USA
- Vincent OConnor, University of Southampton - United Kingdom
- David Dupret, University of Oxford - United Kingdom
- Christopher Linington, University of Glasgow - United Kingdom
- Ziad Mallat, University of Cambridge - United Kingdom
- James A. Huntington, University of Cambridge - United Kingdom
- William Wisden, University of Aberdeen - King´s College - United Kingdom
- Sophia Karagiannis, King´s College London - United Kingdom
- Peter Somogyi, The University of Oxford - United Kingdom
- Marzia Malcangio, King´s College London - United Kingdom
- Hannah J. Gould, King´s College London - United Kingdom
- Anne Dell, Imperial College London - United Kingdom
- Kenneth G. C. Smith, Universal College London - United Kingdom
Research Output
- 17188 Citations
- 241 Publications
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2024
Title A triple cysteine motif as major determinant of the modulation of neuronal KV7 channels by the paracetamol metabolite N-acetyl-p-benzo quinone imine DOI 10.1111/bph.16380 Type Journal Article Author Ray S Journal British Journal of Pharmacology Pages 2851-2868 Link Publication -
2025
Title Linking Transcriptional and Cellular Responses of Human and Murine Pneumococcal Pneumonia DOI 10.1101/2025.02.13.638069 Type Preprint Author Gorki A Pages 2025.02.13.638069 -
2012
Title Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue DOI 10.1038/nm.2757 Type Journal Article Author Kiefer F Journal Nature Medicine Pages 918-925 Link Publication -
2012
Title The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism DOI 10.1016/j.cmet.2012.04.023 Type Journal Article Author Haschemi A Journal Cell Metabolism Pages 813-826 Link Publication -
2012
Title Long-chain n-3 PUFAs reduce adipose tissue and systemic inflammation in severely obese nondiabetic patients: a randomized controlled trial DOI 10.3945/ajcn.112.037432 Type Journal Article Author Itariu B Journal The American Journal of Clinical Nutrition Pages 1137-1149 Link Publication -
2012
Title NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury DOI 10.1093/brain/aws012 Type Journal Article Author Fischer M Journal Brain Pages 886-899 Link Publication -
2012
Title Concomitant facilitation of GABAA receptors and KV7 channels by the non-opioid analgesic flupirtine DOI 10.1111/j.1476-5381.2011.01821.x Type Journal Article Author Klinger F Journal British Journal of Pharmacology Pages 1631-1642 Link Publication -
2012
Title Temporal Dynamics of Parvalbumin-Expressing Axo-axonic and Basket Cells in the Rat Medial Prefrontal Cortex In Vivo DOI 10.1523/jneurosci.3475-12.2012 Type Journal Article Author Massi L Journal The Journal of Neuroscience Pages 16496-16502 Link Publication -
2012
Title Reengineering the Collision Coupling and Diffusion Mode of the A2A-adenosine Receptor PALMITOYLATION IN HELIX 8 RELIEVES CONFINEMENT* DOI 10.1074/jbc.m112.393579 Type Journal Article Author Keuerleber S Journal Journal of Biological Chemistry Pages 42104-42118 Link Publication -
2012
Title Monitoring neutrophils and platelets during casein-induced anaphylaxis in an experimental BALB/c mouse model DOI 10.1111/j.1365-2222.2012.04012.x Type Journal Article Author Krishnamurthy D Journal Clinical & Experimental Allergy Pages 1119-1128 -
2012
Title Interleukin-10: An Anti-Inflammatory Marker To Target Atherosclerotic Lesions via PEGylated Liposomes DOI 10.1021/mp300316n Type Journal Article Author Almer G Journal Molecular Pharmaceutics Pages 175-186 Link Publication -
2012
Title Prospects of Transcript Profiling for mRNAs and MicroRNAs Using Formalin-Fixed and Paraffin-Embedded Dissected Autoptic Multiple Sclerosis Lesions DOI 10.1111/j.1750-3639.2012.00564.x Type Journal Article Author Eisele S Journal Brain Pathology Pages 607-618 Link Publication -
2012
Title An unfolded variant of the major peanut allergen Ara h 2 with decreased anaphylactic potential DOI 10.1111/cea.12031 Type Journal Article Author Starkl P Journal Clinical & Experimental Allergy Pages 1801-1812 Link Publication -
2012
Title Expression of G Protein-Coupled Receptor 19 in Human Lung Cancer Cells Is Triggered by Entry into S-Phase and Supports G2–M Cell-Cycle Progression DOI 10.1158/1541-7786.mcr-12-0139 Type Journal Article Author Kastner S Journal Molecular Cancer Research Pages 1343-1358 Link Publication -
2012
Title Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease DOI 10.1194/jlr.m025445 Type Journal Article Author Amir S Journal Journal of Lipid Research Pages 1316-1326 Link Publication -
2012
Title Functional and physical interactions between P2Y receptors and ion channels DOI 10.1186/2050-6511-13-s1-a61 Type Journal Article Author Gafar H Journal BMC Pharmacology and Toxicology Link Publication -
2012
Title The Thr715Pro variant impairs terminal glycosylation of P-selectin DOI 10.1160/th12-01-0047 Type Journal Article Author Subramanian H Journal Thrombosis and Haemostasis Pages 963-972 Link Publication -
2012
Title VEGF-induced endothelial cell migration requires urokinase receptor (uPAR)-dependent integrin redistribution DOI 10.1093/cvr/cvs017 Type Journal Article Author Alexander R Journal Cardiovascular Research Pages 125-135 Link Publication -
2012
Title Establishing an allergic eczema model employing recombinant house dust mite allergens Der p 1 and Der p 2 in BALB/c mice DOI 10.1111/exd.12015 Type Journal Article Author Szalai K Journal Experimental Dermatology Pages 842-846 Link Publication -
2012
Title The Interferon Stimulated Gene 12 Inactivates Vasculoprotective Functions of NR4A Nuclear Receptors DOI 10.1161/circresaha.111.258814 Type Journal Article Author Papac-Milicevic N Journal Circulation Research Link Publication -
2011
Title Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice DOI 10.1007/s00125-011-2170-0 Type Journal Article Author Kiefer F Journal Diabetologia Pages 2132-2142 Link Publication -
2011
Title Soluble M6P/IGF2R Released by TACE Controls Angiogenesis via Blocking Plasminogen Activation DOI 10.1161/circresaha.110.234732 Type Journal Article Author Leksa V Journal Circulation Research Pages 676-685 Link Publication -
2011
Title Why could passive Immunoglobulin E antibody therapy be safe in clinical oncology? DOI 10.1111/j.1365-2222.2011.03764.x Type Journal Article Author Jensen-Jarolim E Journal Clinical & Experimental Allergy Pages 1337-1340 Link Publication -
2011
Title Signal Integration and Coincidence Detection in the Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) Cascade CONCOMITANT ACTIVATION OF RECEPTOR TYROSINE KINASES AND OF LRP-1 LEADS TO SUSTAINED ERK PHOSPHORYLATION VIA DOWN- DOI 10.1074/jbc.m111.221903 Type Journal Article Author Geetha N Journal Journal of Biological Chemistry Pages 25663-25674 Link Publication -
2011
Title IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA DOI 10.1038/ni.2048 Type Journal Article Author Pichlmair A Journal Nature Immunology Pages 624-630 -
2011
Title Spatio-temporal expression analysis of the calcium-binding protein calumenin in the rodent brain DOI 10.1016/j.neuroscience.2011.11.069 Type Journal Article Author Vasiljevic M Journal Neuroscience Pages 29-41 Link Publication -
2011
Title Pathogenic T cell responses against aquaporin 4 DOI 10.1007/s00401-011-0824-0 Type Journal Article Author Pohl M Journal Acta Neuropathologica Pages 21 Link Publication -
2011
Title Cancer vaccines inducing antibody production: more pros than cons DOI 10.1586/erv.11.105 Type Journal Article Author Jensen-Jarolim E Journal Expert Review of Vaccines Pages 1281-1289 -
2011
Title Osteopontin Is an Activator of Human Adipose Tissue Macrophages and Directly Affects Adipocyte Function DOI 10.1210/en.2010-1328 Type Journal Article Author Zeyda M Journal Endocrinology Pages 2219-2227 Link Publication -
2011
Title The Serotonin Transporter Is an Exclusive Client of the Coat Protein Complex II (COPII) Component SEC24C* DOI 10.1074/jbc.m111.230037 Type Journal Article Author Sucic S Journal Journal of Biological Chemistry Pages 16482-16490 Link Publication -
2011
Title Distribution of M-channel subunits KCNQ2 and KCNQ3 in rat hippocampus DOI 10.1016/j.neuroimage.2011.07.003 Type Journal Article Author Klinger F Journal NeuroImage Pages 761-769 Link Publication -
2011
Title Nucleotides control the excitability of sensory neurons via two P2Y receptors and a bifurcated signaling cascade DOI 10.1016/j.pain.2011.04.016 Type Journal Article Author Yousuf A Journal Pain Pages 1899-1908 Link Publication -
2015
Title The anticonvulsant retigabine is a subtype selective modulator of GABAA receptors DOI 10.1111/epi.12950 Type Journal Article Author Treven M Journal Epilepsia Pages 647-657 Link Publication -
2015
Title Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display DOI 10.1371/journal.pone.0127169 Type Journal Article Author Keller T Journal PLOS ONE Link Publication -
2015
Title Nitration of ß-Lactoglobulin but Not of Ovomucoid Enhances Anaphylactic Responses in Food Allergic Mice DOI 10.1371/journal.pone.0126279 Type Journal Article Author Diesner S Journal PLOS ONE Link Publication -
2015
Title Derivation of a new parametric impulse response matrix utilized for nodal wind load identification by response measurement DOI 10.1016/j.jsv.2014.12.027 Type Journal Article Author Amiri A Journal Journal of Sound and Vibration Pages 101-113 Link Publication -
2014
Title Impact of Age and Metabolic Syndrome on the Adipokine Profile in Childhood and Adult Obesity DOI 10.1055/s-0034-1375647 Type Journal Article Author Weghuber D Journal Experimental and Clinical Endocrinology & Diabetes (Barth) Pages 363-367 -
2014
Title Axonal Targeting of the Serotonin Transporter in Cultured Rat Dorsal Raphe Neurons Is Specified by SEC24C-Dependent Export from the Endoplasmic Reticulum DOI 10.1523/jneurosci.2991-13.2014 Type Journal Article Author Montgomery T Journal The Journal of Neuroscience Pages 6344-6351 Link Publication -
2014
Title The Triggering Receptor Expressed on Myeloid Cells 2 Inhibits Complement Component 1q Effector Mechanisms and Exerts Detrimental Effects during Pneumococcal Pneumonia DOI 10.1371/journal.ppat.1004167 Type Journal Article Author Sharif O Journal PLoS Pathogens Link Publication -
2014
Title Association between the rs342293 polymorphism and adverse cardiac events in patients undergoing percutaneous coronary intervention DOI 10.1160/th13-09-0757 Type Journal Article Author Siller-Matula J Journal Thrombosis and Haemostasis Pages 1060-1066 -
2014
Title Excitation of rat sympathetic neurons via M1 muscarinic receptors independently of Kv7 channels DOI 10.1007/s00424-014-1487-1 Type Journal Article Author Salzer I Journal Pflügers Archiv - European Journal of Physiology Pages 2289-2303 Link Publication -
2014
Title Thymic stromal lymphopoietin is expressed in the intact central nervous system and upregulated in the myelin-degenerative central nervous system DOI 10.1002/glia.22662 Type Journal Article Author Kitic M Journal Glia Pages 1066-1074 Link Publication -
2014
Title Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man DOI 10.1016/j.cell.2014.04.043 Type Journal Article Author Jais A Journal Cell Pages 25-40 Link Publication -
2008
Title After Injection into the Striatum, in Vitro-Differentiated Microglia- and Bone Marrow-Derived Dendritic Cells Can Leave the Central Nervous System via the Blood Stream DOI 10.2353/ajpath.2008.080234 Type Journal Article Author Hochmeister S Journal The American Journal of Pathology Pages 1669-1681 Link Publication -
2008
Title Restricted Collision Coupling of the A2A Receptor Revisited EVIDENCE FOR PHYSICAL SEPARATION OF TWO SIGNALING CASCADES* DOI 10.1074/jbc.m706275200 Type Journal Article Author Charalambous C Journal Journal of Biological Chemistry Pages 9276-9288 Link Publication -
2008
Title Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells DOI 10.1007/s00262-008-0607-1 Type Journal Article Author Karagiannis P Journal Cancer Immunology, Immunotherapy Pages 915-930 Link Publication -
2008
Title Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A–induced hepatitis DOI 10.1002/hep.22401 Type Journal Article Author Beldi G Journal Hepatology Pages 841-852 Link Publication -
2008
Title A membrane network of receptors and enzymes for adenine nucleotides and nucleosides DOI 10.1186/1471-2210-8-s1-a40 Type Journal Article Author Schicker K Journal BMC Pharmacology Link Publication -
2008
Title The non-opioid analgesic flupirtine is a modulator of GABAA receptors involved in pain sensation DOI 10.1186/1471-2210-8-s1-a14 Type Journal Article Author Popovici F Journal BMC Pharmacology Link Publication -
2008
Title CC Chemokine and CC Chemokine Receptor Profiles in Visceral and Subcutaneous Adipose Tissue Are Altered in Human Obesity DOI 10.1210/jc.2007-2630 Type Journal Article Author Huber J Journal The Journal of Clinical Endocrinology & Metabolism Pages 3215-3221 -
2007
Title Cross-Regulation of Carbon Monoxide and the Adenosine A2a Receptor in Macrophages DOI 10.4049/jimmunol.178.9.5921 Type Journal Article Author Haschemi A Journal The Journal of Immunology Pages 5921-5929 Link Publication -
2007
Title Heme oxygenase and carbon monoxide initiate homeostatic signaling DOI 10.1007/s00109-007-0276-0 Type Journal Article Author Bilban M Journal Journal of Molecular Medicine Pages 267-279 -
2007
Title Osteopontin Expression in Human and Murine Obesity: Extensive Local Up-Regulation in Adipose Tissue but Minimal Systemic Alterations DOI 10.1210/en.2007-1312 Type Journal Article Author Kiefer F Journal Endocrinology Pages 1350-1357 -
2011
Title Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse DOI 10.1172/jci44751 Type Journal Article Author Kerjaschki D Journal Journal of Clinical Investigation Pages 2000-2012 Link Publication -
2011
Title Functional Dissection of the TBK1 Molecular Network DOI 10.1371/journal.pone.0023971 Type Journal Article Author Goncalves A Journal PLoS ONE Link Publication -
2011
Title Heating Affects Structure, Enterocyte Adsorption and Signalling, As Well as Immunogenicity of the Peanut Allergen Ara h 2 DOI 10.2174/1874838401104010024 Type Journal Article Author Starkl P Journal The Open Allergy Journal Pages 24-34 Link Publication -
2011
Title Cross-Talk Between Interferon-? and Hedgehog Signaling Regulates Adipogenesis DOI 10.2337/db10-1628 Type Journal Article Author Todoric J Journal Diabetes Pages 1668-1676 Link Publication -
2011
Title Regulation of GABAA Receptor Dynamics by Interaction with Purinergic P2X2 Receptors* DOI 10.1074/jbc.m110.165282 Type Journal Article Author Shrivastava A Journal Journal of Biological Chemistry Pages 14455-14468 Link Publication -
2011
Title Carbon Monoxide Induced PPAR? SUMOylation and UCP2 Block Inflammatory Gene Expression in Macrophages DOI 10.1371/journal.pone.0026376 Type Journal Article Author Haschemi A Journal PLoS ONE Link Publication -
2011
Title Oxidative damage in multiple sclerosis lesions DOI 10.1093/brain/awr128 Type Journal Article Author Haider L Journal Brain Pages 1914-1924 Link Publication -
2011
Title GABAA Receptors: Post-Synaptic Co-Localization and Cross-Talk with Other Receptors DOI 10.3389/fncel.2011.00007 Type Journal Article Author Shrivastava A Journal Frontiers in Cellular Neuroscience Pages 7 Link Publication -
2011
Title Phylogenetic discordance of human and canine carcinoembryonic antigen (CEA, CEACAM) families, but striking identity of the CEA receptors will impact comparative oncology studies. DOI 10.1371/currents.rrn1223 Type Journal Article Author Weichselbaumer M Journal PLoS Currents: Tree of Life Link Publication -
2011
Title Facilitation of transmitter release from rat sympathetic neurons via presynaptic P2Y1 receptors DOI 10.1111/j.1476-5381.2011.01466.x Type Journal Article Author Chandaka G Journal British Journal of Pharmacology Pages 1522-1533 Link Publication -
2010
Title Haem arginate infusion stimulates haem oxygenase-1 expression in healthy subjects DOI 10.1111/j.1476-5381.2010.00990.x Type Journal Article Author Doberer D Journal British Journal of Pharmacology Pages 1751-1762 Link Publication -
2010
Title The High Affinity IgE Receptor FceRI Is Expressed by Human Intestinal Epithelial Cells DOI 10.1371/journal.pone.0009023 Type Journal Article Author Untersmayr E Journal PLoS ONE Link Publication -
2010
Title Increased bone resorption and impaired bone microarchitecture in short-term and extended high-fat diet–induced obesity DOI 10.1016/j.metabol.2009.11.023 Type Journal Article Author Patsch J Journal Metabolism Pages 243-249 Link Publication -
2010
Title P2Y1 receptors mediate an activation of neuronal calcium-dependent K+ channels DOI 10.1113/jphysiol.2010.193367 Type Journal Article Author Schicker K Journal The Journal of Physiology Pages 3713-3725 Link Publication -
2010
Title Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination DOI 10.1007/s00401-010-0704-z Type Journal Article Author Sharma R Journal Acta Neuropathologica Pages 223-236 Link Publication -
2010
Title Imaging of Mobile Long-lived Nanoplatforms in the Live Cell Plasma Membrane* DOI 10.1074/jbc.m110.182121 Type Journal Article Author Brameshuber M Journal Journal of Biological Chemistry Pages 41765-41771 Link Publication -
2010
Title Neutralization of Osteopontin Inhibits Obesity-Induced Inflammation and Insulin Resistance DOI 10.2337/db09-0404 Type Journal Article Author Kiefer F Journal Diabetes Pages 935-946 Link Publication -
2010
Title From cradle to twilight: The carboxyl terminus directs the fate of the A2A-adenosine receptor DOI 10.1016/j.bbamem.2010.05.009 Type Journal Article Author Keuerleber S Journal Biochimica et Biophysica Acta (BBA) - Biomembranes Pages 1350-1357 Link Publication -
2010
Title Transcriptome analysis of human cancer reveals a functional role of Heme Oxygenase-1 in tumor cell adhesion DOI 10.1186/1476-4598-9-200 Type Journal Article Author Tauber S Journal Molecular Cancer Pages 200 Link Publication -
2010
Title Proximal human FOXP3 promoter transactivated by NF-?B and negatively controlled by feedback loop and SP3 DOI 10.1016/j.molimm.2010.04.002 Type Journal Article Author Eckerstorfer P Journal Molecular Immunology Pages 2094-2102 Link Publication -
2010
Title Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity DOI 10.1016/j.cell.2010.04.018 Type Journal Article Author Dixit E Journal Cell Pages 668-681 Link Publication -
2010
Title Newly identified adipose tissue macrophage populations in obesity with distinct chemokine and chemokine receptor expression DOI 10.1038/ijo.2010.103 Type Journal Article Author Zeyda M Journal International Journal of Obesity Pages 1684-1694 -
2010
Title Drosophila Genome-wide Obesity Screen Reveals Hedgehog as a Determinant of Brown versus White Adipose Cell Fate DOI 10.1016/j.cell.2009.12.027 Type Journal Article Author Pospisilik J Journal Cell Pages 148-160 Link Publication -
2010
Title Nitration of the Egg-Allergen Ovalbumin Enhances Protein Allergenicity but Reduces the Risk for Oral Sensitization in a Murine Model of Food Allergy DOI 10.1371/journal.pone.0014210 Type Journal Article Author Untersmayr E Journal PLoS ONE Link Publication -
2010
Title The High-Affinity Binding Site for Tricyclic Antidepressants Resides in the Outer Vestibule of the Serotonin Transporter DOI 10.1124/mol.110.067538 Type Journal Article Author Sarker S Journal Molecular Pharmacology Pages 1026-1035 Link Publication -
2009
Title Direct Observation and Quantitative Analysis of Lck Exchange between Plasma Membrane and Cytosol in Living T Cells* DOI 10.1074/jbc.m109.025981 Type Journal Article Author Zimmermann L Journal Journal of Biological Chemistry Pages 6063-6070 Link Publication -
2009
Title Genetically Encoded Förster Resonance Energy Transfer Sensors for the Conformation of the Src Family Kinase Lck DOI 10.4049/jimmunol.0802639 Type Journal Article Author Paster W Journal The Journal of Immunology Pages 2160-2167 Link Publication -
2009
Title Sequential Cooperation of CD2 and CD48 in the Buildup of the Early TCR Signalosome DOI 10.4049/jimmunol.0800691 Type Journal Article Author Muhammad A Journal The Journal of Immunology Pages 7672-7680 Link Publication -
2009
Title The TLR-independent DNA recognition pathway in murine macrophages: Ligand features and molecular signature DOI 10.1002/eji.200939344 Type Journal Article Author Karayel E Journal European Journal of Immunology Pages 1929-1936 Link Publication -
2009
Title P-selectin mRNA is maintained in platelet concentrates stored at 4°C DOI 10.1111/j.1537-2995.2008.02073.x Type Journal Article Author Stiegler G Journal Transfusion Pages 921-927 Link Publication -
2009
Title An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome DOI 10.1038/ni.1702 Type Journal Article Author Bürckstümmer T Journal Nature Immunology Pages 266-272 -
2009
Title Liver X receptors interfere with cytokine-induced proliferation and cell survival in normal and leukemic lymphocytes DOI 10.1189/jlb.1008663 Type Journal Article Author Geyeregger R Journal Journal of Leukocyte Biology Pages 1039-1048 -
2009
Title Experimental immunotherapeutic approaches for atherosclerosis DOI 10.1016/j.clim.2009.07.009 Type Journal Article Author Amir S Journal Clinical Immunology Pages 66-79 Link Publication -
2008
Title Facilitation of transmitter release from rat sympathetic neurons via presynaptic P2Y1 receptors DOI 10.1186/1471-2210-8-s1-a8 Type Journal Article Author Chandaka G Journal BMC Pharmacology Link Publication -
2008
Title A membrane network of receptors and enzymes for adenine nucleotides and nucleosides DOI 10.1016/j.bbamcr.2008.09.014 Type Journal Article Author Schicker K Journal Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Pages 325-334 Link Publication -
2008
Title Dose-dependent food allergy induction against ovalbumin under acid-suppression: A murine food allergy model DOI 10.1016/j.imlet.2008.08.006 Type Journal Article Author Diesner S Journal Immunology Letters Pages 45-51 Link Publication -
2024
Title Deconstructing CTL-mediated autoimmunity through weak TCR-cross-reactivity towards highly abundant self-antigen DOI 10.1101/2024.08.17.608371 Type Preprint Author Plach A Pages 2024.08.17.608371 Link Publication -
2024
Title TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation DOI 10.1126/sciadv.adj4632 Type Journal Article Author Mühlgrabner V Journal Science Advances Link Publication -
2023
Title Monomeric agonist peptide/MHCII complexes activate T-cells in an autonomous fashion DOI 10.1101/2023.03.13.532401 Type Preprint Author Platzer R Pages 2023.03.13.532401 Link Publication -
2023
Title Monomeric agonist peptide/MHCII complexes activate T-cells in an autonomous fashion DOI 10.15252/embr.202357842 Type Journal Article Author Platzer R Journal EMBO reports Link Publication -
2017
Title Long term storage in liquid nitrogen leads to only minor phenotypic and gene expression changes in the mammary carcinoma model cell line BT474 DOI 10.18632/oncotarget.16623 Type Journal Article Author Fazekas J Journal Oncotarget Pages 35076-35087 Link Publication -
2017
Title First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment DOI 10.1016/j.celrep.2017.01.071 Type Journal Article Author Saluzzo S Journal Cell Reports Pages 1893-1905 Link Publication -
2017
Title Janus-faced Acrolein prevents allergy but accelerates tumor growth by promoting immunoregulatory Foxp3+ cells: Mouse model for passive respiratory exposure DOI 10.1038/srep45067 Type Journal Article Author Roth-Walter F Journal Scientific Reports Pages 45067 Link Publication -
2017
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Title Extracellular Purine Metabolism Is the Switchboard of Immunosuppressive Macrophages and a Novel Target to Treat Diseases With Macrophage Imbalances DOI 10.3389/fimmu.2018.00852 Type Journal Article Author Ohradanova-Repic A Journal Frontiers in Immunology Pages 852 Link Publication -
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Title Mechanism of hERG Channel Block by the Psychoactive Indole Alkaloid Ibogaine DOI 10.1124/jpet.113.209643 Type Journal Article Author Thurner P Journal The Journal of Pharmacology and Experimental Therapeutics Pages 346-358 -
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Title Protamine nanoparticles with CpG-oligodeoxynucleotide prevent an allergen-induced Th2-response in BALB/c mice DOI 10.1016/j.ejpb.2013.03.003 Type Journal Article Author Pali-Schöll I Journal European Journal of Pharmaceutics and Biopharmaceutics Pages 656-664 -
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Title Experimental characterization of the human non-sequence-specific nucleic acid interactome DOI 10.1186/gb-2013-14-7-r81 Type Journal Article Author Dürnberger G Journal Genome Biology Link Publication -
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Title The parvalbumin-positive interneurons in the mouse dentate gyrus express GABAA receptor subunits alpha1, beta2, and delta along their extrasynaptic cell membrane DOI 10.1016/j.neuroscience.2013.09.019 Type Journal Article Author Milenkovic I Journal Neuroscience Pages 80-96 -
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Title Enhanced Lymph Vessel Density, Remodeling, and Inflammation Are Reflected by Gene Expression Signatures in Dermal Lymphatic Endothelial Cells in Type 2 Diabetes DOI 10.2337/db12-0844 Type Journal Article Author Haemmerle M Journal Diabetes Pages 2509-2529 Link Publication -
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Title Switching the Clientele DOI 10.1074/jbc.m112.408237 Type Journal Article Author Sucic S Journal Journal of Biological Chemistry Pages 5330-5341 Link Publication -
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Title Recruitment of a Cytoplasmic Chaperone Relay by the A2A Adenosine Receptor* DOI 10.1074/jbc.m113.464776 Type Journal Article Author Bergmayr C Journal Journal of Biological Chemistry Pages 28831-28844 Link Publication -
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Title Impaired Local Production of Proresolving Lipid Mediators in Obesity and 17-HDHA as a Potential Treatment for Obesity-Associated Inflammation DOI 10.2337/db12-0828 Type Journal Article Author Neuhofer A Journal Diabetes Pages 1945-1956 Link Publication -
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Title VGluT3+ Primary Afferents Play Distinct Roles in Mechanical and Cold Hypersensitivity Depending on Pain Etiology DOI 10.1523/jneurosci.2157-14.2014 Type Journal Article Author Draxler P Journal The Journal of Neuroscience Pages 12015-12028 Link Publication -
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Title The Scavenger Receptor CD36 Downmodulates the Early Inflammatory Response while Enhancing Bacterial Phagocytosis during Pneumococcal Pneumonia DOI 10.4049/jimmunol.1202270 Type Journal Article Author Sharif O Journal The Journal of Immunology Pages 5640-5648 Link Publication -
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Title Intrastriatal injection of interleukin-1 beta triggers the formation of neuromyelitis optica-like lesions in NMO-IgG seropositive rats DOI 10.1186/2051-5960-1-5 Type Journal Article Author Kitic M Journal Acta Neuropathologica Communications Pages 5 Link Publication -
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Title Functional Rescue of a Misfolded Drosophila melanogaster Dopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones* ? DOI 10.1074/jbc.m116.737551 Type Journal Article Author Kasture A Journal Journal of Biological Chemistry Pages 20876-20890 Link Publication -
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Title Type I interferon promotes alveolar epithelial type II cell survival during pulmonary Streptococcus pneumoniae infection and sterile lung injury in mice DOI 10.1002/eji.201546201 Type Journal Article Author Maier B Journal European Journal of Immunology Pages 2175-2186 Link Publication -
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Title Membrane coordination of receptors and channels mediating the inhibition of neuronal ion currents by ADP DOI 10.1007/s11302-016-9516-5 Type Journal Article Author Gafar H Journal Purinergic Signalling Pages 497-507 Link Publication -
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Title Divisions of Identified Parvalbumin-Expressing Basket Cells during Working Memory-Guided Decision Making DOI 10.1016/j.neuron.2016.08.010 Type Journal Article Author Lagler M Journal Neuron Pages 1390-1401 Link Publication -
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Title The brain-tumor related protein podoplanin regulates synaptic plasticity and hippocampus-dependent learning and memory DOI 10.1080/07853890.2016.1219455 Type Journal Article Author Cicvaric A Journal Annals of Medicine Pages 652-668 Link Publication -
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Title Human but Not Mouse Adipogenesis Is Critically Dependent on LMO3 DOI 10.1016/j.cmet.2013.05.020 Type Journal Article Author Lindroos J Journal Cell Metabolism Pages 62-74 Link Publication -
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Title IgE-based Immunotherapy of Cancer -A Comparative Oncology Approach DOI 10.4172/2157-2518.1000176 Type Journal Article Author Singer J Journal Journal of Carcinogenesis & Mutagenesis Pages 1000176 Link Publication -
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Title The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production DOI 10.1016/j.virol.2014.05.016 Type Journal Article Author Eberle C Journal Virology Pages 34-41 Link Publication -
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Title Papain Degrades Tight Junction Proteins of Human Keratinocytes In Vitro and Sensitizes C57BL/6 Mice via the Skin Independent of its Enzymatic Activity or TLR4 Activation DOI 10.1038/jid.2015.58 Type Journal Article Author Stremnitzer C Journal Journal of Investigative Dermatology Pages 1790-1800 Link Publication -
2015
Title Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9 DOI 10.1093/brain/awv102 Type Journal Article Author Lindner M Journal Brain Pages 1875-1893 Link Publication -
2015
Title Crosstalk of carcinoembryonic antigen and transforming growth factor-ß via their receptors: comparing human and canine cancer DOI 10.1007/s00262-015-1684-6 Type Journal Article Author Jensen-Jarolim E Journal Cancer Immunology, Immunotherapy Pages 531-537 Link Publication -
2015
Title Translating clinical trials from human to veterinary oncology and back DOI 10.1186/s12967-015-0631-9 Type Journal Article Author Fürdös I Journal Journal of Translational Medicine Pages 265 Link Publication -
2015
Title d Subunit-containing GABAA receptors are preferred targets for the centrally acting analgesic flupirtine DOI 10.1111/bph.13262 Type Journal Article Author Klinger F Journal British Journal of Pharmacology Pages 4946-4958 Link Publication -
2020
Title Targeting foam cell formation in inflammatory brain diseases by the histone modifier MS-275 DOI 10.1002/acn3.51200 Type Journal Article Author Zierfuss B Journal Annals of Clinical and Translational Neurology Pages 2161-2177 Link Publication -
2020
Title Unscrambling fluorophore blinking for comprehensive cluster detection via photoactivated localization microscopy DOI 10.1038/s41467-020-18726-9 Type Journal Article Author Platzer R Journal Nature Communications Pages 4993 Link Publication -
2020
Title Functional Impact of the G279S Substitution in the Adenosine A1-Receptor (A1R-G279S7.44), a Mutation Associated with Parkinson’s Disease DOI 10.1124/mol.120.000003 Type Journal Article Author Nasrollahi-Shirazi S Journal Molecular Pharmacology Pages 250-266 Link Publication -
2020
Title Neutrophil Extracellular Traps Induce MCP-1 at the Culprit Site in ST-Segment Elevation Myocardial Infarction DOI 10.3389/fcell.2020.564169 Type Journal Article Author Hofbauer T Journal Frontiers in Cell and Developmental Biology Pages 564169 Link Publication -
2019
Title The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection DOI 10.1101/573253 Type Preprint Author Moskovskich A Pages 573253 Link Publication -
2019
Title Deciphering the microbiome shift during fermentation of medicinal plants DOI 10.1038/s41598-019-49799-2 Type Journal Article Author Köberl M Journal Scientific Reports Pages 13461 Link Publication